44 citations · 103 across the 5 of their papers we have counts for
5 papers
A mechanistic model quantifies artemisinin-induced parasite growth retardation in blood-stage Plasmodium falciparum infection
Pengxing Cao, Nectarios Klonis, Sophie Zaloumis +6
Falciparum malaria is a major parasitic disease causing widespread morbidity and mortality globally. Artemisinin derivatives---the most effective and widely-used antimalarials that…
A dynamic stress model explains the delayed drug effect in artemisinin treatment of Plasmodium falciparum
Pengxing Cao, Nectarios Klonis, Sophie Zaloumis +8
Artemisinin resistance constitutes a major threat to the continued success of control programs for malaria. With alternative antimalarial drugs not yet available, improving our und…
On the role of T cells in determining recovery time from influenza virus infection
Pengxing Cao, Zhongfang Wang, Ada W. C. Yan +5
Myriad experiments have identified an important role for T cell response mechanisms in determining recovery from influenza A virus infection. Animal models of influenza…
Modelling cross-reactivity and memory in the cellular adaptive immune response to influenza infection in the host
Ada W. C. Yan, Pengxing Cao, Jane M. Heffernan +5
The cellular adaptive immune response plays a key role in resolving influenza infection. Experiments where individuals are successively infected with different strains within a sho…
Data-driven modelling of the inositol trisphosphate receptor (IPR) and its role in calcium induced calcium release (CICR)
Ivo Siekmann, Pengxing Cao, James Sneyd +1
We give a review of the current state of the art of data-driven modelling of the inositol trisphosphate receptor (IPR). After explaining that the IPR plays a crucial role as a cent…