output
20102025
most citedBayesian Test for Colocalisation Between Pairs of Genetic Association Studies Using Summary Statistics

4.8k citations

18 papers

physics.med-ph2025★ 2 cited

Millennium Pathways for Tractography: 40 grand challenges to shape the future of tractography

Maxime Descoteaux, Kurt G. Schilling, Dogu Baran Aydogan +44

In the spirit of the historic Millennium Prize Problems that heralded a new era for mathematics, the newly formed International Society for Tractography (IST) has launched the Mill…

q-bio.NC2025★ 4 cited

Small brains but big challenges: white matter tractography in early life samples

Jessica Dubois, Mareike Grotheer, Joseph Yuan-Mou Yang +3

In the human brain, white matter development is a complex and long-lasting process involving intermingling micro-and macrostructural mechanisms, such as fiber growth, pruning and m…

physics.med-ph2024★ 2 cited

MICCAI-CDMRI 2023 QuantConn Challenge Findings on Achieving Robust Quantitative Connectivity through Harmonized Preprocessing of Diffusion MRI

Nancy R. Newlin, Kurt Schilling, Serge Koudoro +33

White matter alterations are increasingly implicated in neurological diseases and their progression. International-scale studies use diffusion-weighted magnetic resonance imaging (…

cs.CV2024★ 7 cited

Harmonizing Flows: Leveraging normalizing flows for unsupervised and source-free MRI harmonization

Farzad Beizaee, Gregory A. Lodygensky, Chris L. Adamson +5

Lack of standardization and various intrinsic parameters for magnetic resonance (MR) image acquisition results in heterogeneous images across different sites and devices, which adv…

physics.med-ph2024★ 14 cited

A novel optical assay system for bilirubin concentration measurement in whole blood

Jean Pierre Ndabakuranye, Anushi E. Rajapaksa, Genia Burchall +3

As a biomarker for liver disease, bilirubin has been utilized in prognostic scoring systems for cirrhosis. While laboratory-based methods are used to determine bilirubin levels in…

cs.CY2020★ 9 cited

From climate change to pandemics: decision science can help scientists have impact

Christopher M. Baker, Patricia T. Campbell, Iadine Chades +8

Scientific knowledge and advances are a cornerstone of modern society. They improve our understanding of the world we live in and help us navigate global challenges including emerg…

stat.AP2019★ 128 cited

Contextual Stress and Maternal Sensitivity: A Meta-Analytic Review of Stress Associations with the Maternal Behavior Q-Sort in Observational Studies

Anna Tudehope Booth, Jacqui Macdonald, George Youssef

Maternal sensitivity is a modifiable determinant of infant attachment security and a precursor to optimal child development. Contextual stressors undermine sensitivity, but researc…

q-bio.TO2018★ 7 cited

Mathematical modelling indicates that lower activity of the haemostatic system in neonates is primarily due to lower prothrombin concentration

Ivo Siekmann, Stefan Bjelosevic, Kerry Landman +3

Haemostasis is governed by a highly complex system of interacting proteins. Due to the central role of thrombin, thrombin generation and specifically the thrombin generation curve…

cs.DC2018

CRUM: Checkpoint-Restart Support for CUDA's Unified Memory

Rohan Garg, Apoore Mohan, Michael Sullivan +1

Unified Virtual Memory (UVM) was recently introduced on recent NVIDIA GPUs. Through software and hardware support, UVM provides a coherent shared memory across the entire heterogen…

q-bio.PE2017

Sequential infection experiments for quantifying innate and adaptive immunity during influenza infection

Ada W. C. Yan, Sophie G. Zaloumis, Julie A. Simpson +1

Laboratory models are often used to understand the interaction of related pathogens via host immunity. For example, recent experiments where ferrets were exposed to two influenza s…

q-bio.PE2017★ 12 cited

A mechanistic model quantifies artemisinin-induced parasite growth retardation in blood-stage Plasmodium falciparum infection

Pengxing Cao, Nectarios Klonis, Sophie Zaloumis +6

Falciparum malaria is a major parasitic disease causing widespread morbidity and mortality globally. Artemisinin derivatives---the most effective and widely-used antimalarials that…

q-bio.PE2016★ 26 cited

A biological model of scabies infection dynamics and treatment explains why mass drug administration does not lead to elimination

M. Lydeamore, P. T. Campbell, D. G. Regan +7

Despite a low global prevalence, infections with Sarcoptes scabiei, or scabies, are still common in remote communities such as in northern Australia and the Solomon Islands. Mass d…

stat.AP2016★ 3 cited

Bayesian modelling of lung function data from multiple-breath washout tests

Robert K. Mahar, John B. Carlin, Sarath Ranganathan +3

Paediatric respiratory researchers have widely adopted the multiple-breath washout (MBW) test because it allows assessment of lung function in unsedated infants and is well suited…

q-bio.PE2016★ 15 cited

A dynamic stress model explains the delayed drug effect in artemisinin treatment of Plasmodium falciparum

Pengxing Cao, Nectarios Klonis, Sophie Zaloumis +8

Artemisinin resistance constitutes a major threat to the continued success of control programs for malaria. With alternative antimalarial drugs not yet available, improving our und…

q-bio.CB2016★ 44 cited

On the role of T cells in determining recovery time from influenza virus infection

Pengxing Cao, Zhongfang Wang, Ada W. C. Yan +5

Myriad experiments have identified an important role for T cell response mechanisms in determining recovery from influenza A virus infection. Animal models of influenza…

q-bio.PE2016★ 12 cited

Periodic solutions in an SIRWS model with immune boosting and cross-immunity

Tiffany Leung, Barry D. Hughes, Federico Frascoli +1

Incidence of whooping cough, an infection caused by Bordetella pertussis and Bordetella parapertussis, has been on the rise since the 1980s in many countries. Immunological interac…

q-bio.GN2013★ 4.8k cited

Bayesian Test for Colocalisation Between Pairs of Genetic Association Studies Using Summary Statistics

Claudia Giambartolomei, Damjan Vukcevic, Eric E. Schadt +4

Genetic association studies, in particular the genome-wide association study design, have provided a wealth of novel insights into the aetiology of a wide range of human diseases a…

hep-ph2010★ 26 cited

PHOTOS Interface in C++; Technical and Physics Documentation

N. Davidson, T. Przedzinski, Z. Was

For five years now, PHOTOS Monte Carlo for bremsstrahlung in the decay of particles and resonances has been available with an interface to the C++ HepMC event record. The main purp…