2 papers
q-bio.PE2017
A mechanistic model quantifies artemisinin-induced parasite growth retardation in blood-stage Plasmodium falciparum infection
Pengxing Cao, Nectarios Klonis, Sophie Zaloumis +6
Falciparum malaria is a major parasitic disease causing widespread morbidity and mortality globally. Artemisinin derivatives---the most effective and widely-used antimalarials that…
q-bio.PE2016
A dynamic stress model explains the delayed drug effect in artemisinin treatment of Plasmodium falciparum
Pengxing Cao, Nectarios Klonis, Sophie Zaloumis +8
Artemisinin resistance constitutes a major threat to the continued success of control programs for malaria. With alternative antimalarial drugs not yet available, improving our und…