693 citations
- Hospital for Sick ChildrenCA15 papers
- University of TorontoCA14 papers
- Institute for Clinical Evaluative SciencesCA7 papers
- Public Health OntarioCA6 papers
- University College LondonGB6 papers
- Bayer (United Kingdom)GB2 papers
- Centre National de la Recherche ScientifiqueFR2 papers
- Health Economics and Outcomes Research (United Kingdom)GB2 papers
- Johns Hopkins UniversityUS2 papers
- Laboratoire Psychologie de la PerceptionFR2 papers
- McGill University Health CentreCA2 papers
- Stanford UniversityUS2 papers
6 papers · 1 filter
Effect modification and non-collapsibility leads to conflicting treatment decisions: a review of marginal and conditional estimands and recommendations for decision-making
David M. Phillippo, Antonio Remiro-Azócar, Anna Heath +4
Effect modification occurs when a covariate alters the relative effectiveness of treatment compared to control. It is widely understood that, when effect modification is present, t…
Methodological considerations for novel approaches to covariate-adjusted indirect treatment comparisons
Antonio Remiro-Azócar, Anna Heath, Gianluca Baio
We examine four important considerations in the development of covariate adjustment methodologies for indirect treatment comparisons. Firstly, we consider potential advantages of w…
Model-based standardization using multiple imputation
Antonio Remiro-Azócar, Anna Heath, Gianluca Baio
When studying the association between treatment and a clinical outcome, a parametric multivariable model of the conditional outcome expectation is often used to adjust for covariat…
Parametric G-computation for Compatible Indirect Treatment Comparisons with Limited Individual Patient Data
Antonio Remiro-Azócar, Anna Heath, Gianluca Baio
Population adjustment methods such as matching-adjusted indirect comparison (MAIC) are increasingly used to compare marginal treatment effects when there are cross-trial difference…
Conflating marginal and conditional treatment effects: Comments on 'Assessing the performance of population adjustment methods for anchored indirect comparisons: A simulation study'
Antonio Remiro-Azócar, Anna Heath, Gianluca Baio
In this commentary, we highlight the importance of: (1) carefully considering and clarifying whether a marginal or conditional treatment effect is of interest in a population-adjus…
Effect modification in anchored indirect treatment comparisons: Comments on "Matching-adjusted indirect comparisons: Application to time-to-event data"
Antonio Remiro-Azócar, Anna Heath, Gianluca Baio
This commentary regards a recent simulation study conducted by Aouni, Gaudel-Dedieu and Sebastien, evaluating the performance of different versions of matching-adjusted indirect co…