30 citations
2 papers
q-bio.QM2014★ 30 cited
In Silico Derivation of HLA-Specific Alloreactivity Potential from Whole Exome Sequencing of Stem Cell Transplant Donors and Recipients: Understanding the Quantitative Immuno-biology of Allogeneic Transplantation
Max Jameson-Lee, Vishal Koparde, Phil Griffith +12
Donor T cell mediated graft vs. host effects may result from the aggregate alloreactivity to minor histocompatibility antigens (mHA) presented by the HLA in each donor-recipient pa…
q-bio.OT2014★ 20 cited
Stem Cell Transplantation As A Dynamical System: Are Clinical Outcomes Deterministic?
Amir A Toor, Jared D Kobulnicky, Salman Salman +14
Outcomes in stem cell transplantation (SCT) are modeled using probability theory. However the clinical course following SCT appears to demonstrate many characteristics of dynamical…