activity
20142018
most citedIn Silico Derivation of HLA-Specific Alloreactivity Potential from Whole Exome Sequencing of Stem Cell Transplant Donors and Recipients: Understanding the Quantitative Immuno-biology of Allogeneic Transplantation

30 citations · 75 across the 9 of their papers we have counts for

collaborators

9 papers

cs.CV2018

Deep CNN Frame Interpolation with Lessons Learned from Natural Language Processing

Kian Ghodoussi, Nihar Sheth, Zane Durante +1

A major area of growth within deep learning has been the study and implementation of convolutional neural networks. The general explanation within the deep learning community of th…

q-bio.QM2016★ 25 cited

Dynamical System Modeling to Simulate Donor T Cell Response to Whole Exome Sequencing-Derived Recipient Peptides: Understanding Randomness in Clinical Outcomes Following Stem Cell Transplantation

V Koparde, B Abdul Razzaq, T Suntum +12

Alloreactivity following stem cell transplantation (SCT) is difficult to predict in patients undergoing transplantation from HLA matched donors. In this study we performed whole ex…

q-bio.OT2015

Massive Multi-Omics Microbiome Database (M3DB): A Scalable Data Warehouse and Analytics Platform for Microbiome Datasets

Shaun W. Norris, Steven P. Bradley, Hardik I. Parikh +1

Massive Multi-Omics Microbiome Database (M3DB) is a data warehousing and analytics solution designed to handle diverse, complex, and unprecedented volumes of sequence and taxonomic…

q-bio.GN2015

MEEPTOOLS: A maximum expected error based FASTQ read filtering and trimming toolkit

Vishal N. Koparde, Hardik I. Parikh, Steven P. Bradley +1

Next generation sequencing technology rapidly produces massive volume of data and quality control of this sequencing data is essential to any genomic analysis. Here we present MEEP…

q-bio.GN2015

MeFiT: Merging and Filtering Tool for Illumina Paired-End Reads for 16S rRNA Amplicon Sequencing

Hardik I. Parikh, Vishal N. Koparde, Steven P. Bradley +2

Recent advances in next-generation sequencing have revolutionized genomic research. 16S rRNA amplicon sequencing using paired-end sequencing on the MiSeq platform from Illumina, In…

q-bio.CB2015

Dynamical System Modeling to Simulate Donor T Cell Response to Whole Exome Sequencing-Derived Recipient Peptides Demonstrates Different Alloreactivity Potential In HLA-Matched and Mismatched Donor-Recipient Pairs

B. Abdul Razzaq, A. Scalora, V. Koparde +14

Stem cell transplants may be considered as dynamical systems to allow sequence differences across the exomes of the transplant donors and recipients to be used to simulate an allor…

q-bio.QM2014★ 30 cited

In Silico Derivation of HLA-Specific Alloreactivity Potential from Whole Exome Sequencing of Stem Cell Transplant Donors and Recipients: Understanding the Quantitative Immuno-biology of Allogeneic Transplantation

Max Jameson-Lee, Vishal Koparde, Phil Griffith +12

Donor T cell mediated graft vs. host effects may result from the aggregate alloreactivity to minor histocompatibility antigens (mHA) presented by the HLA in each donor-recipient pa…

q-bio.OT2014★ 20 cited

Stem Cell Transplantation As A Dynamical System: Are Clinical Outcomes Deterministic?

Amir A Toor, Jared D Kobulnicky, Salman Salman +14

Outcomes in stem cell transplantation (SCT) are modeled using probability theory. However the clinical course following SCT appears to demonstrate many characteristics of dynamical…

q-bio.GN2014

Whole Exome Sequencing to Estimate Alloreactivity Potential Between Donors and Recipients in Stem Cell Transplantation

Juliana K. Sampson, Nihar U. Sheth, Vishal N. Koparde +10

Whole exome sequencing was performed on HLA-matched stem cell donors and transplant recipients to measure sequence variation contributing to minor histocompatibility antigen differ…