most citedIn Silico Derivation of HLA-Specific Alloreactivity Potential from Whole Exome Sequencing of Stem Cell Transplant Donors and Recipients: Understanding the Quantitative Immuno-biology of Allogeneic Transplantation

30 citations · 52 across the 4 of their papers we have counts for

collaborators

4 papers

q-bio.CB2015

Dynamical System Modeling to Simulate Donor T Cell Response to Whole Exome Sequencing-Derived Recipient Peptides Demonstrates Different Alloreactivity Potential In HLA-Matched and Mismatched Donor-Recipient Pairs

B. Abdul Razzaq, A. Scalora, V. Koparde +14

Stem cell transplants may be considered as dynamical systems to allow sequence differences across the exomes of the transplant donors and recipients to be used to simulate an allor…

q-bio.QM2014★ 2 cited

Dynamical System Modeling Of Immune Reconstitution Following Allogeneic Stem Cell Transplantation Identifies Patients At Risk For Adverse Outcomes

Amir A. Toor, Roy T. Sabo, Catherine H. Roberts +17

Systems that evolve over time and follow mathematical laws as they do so, are called dynamical systems. Lymphocyte recovery and clinical outcomes in 41 allograft recipients conditi…

q-bio.QM2014★ 30 cited

In Silico Derivation of HLA-Specific Alloreactivity Potential from Whole Exome Sequencing of Stem Cell Transplant Donors and Recipients: Understanding the Quantitative Immuno-biology of Allogeneic Transplantation

Max Jameson-Lee, Vishal Koparde, Phil Griffith +12

Donor T cell mediated graft vs. host effects may result from the aggregate alloreactivity to minor histocompatibility antigens (mHA) presented by the HLA in each donor-recipient pa…

q-bio.OT2014★ 20 cited

Stem Cell Transplantation As A Dynamical System: Are Clinical Outcomes Deterministic?

Amir A Toor, Jared D Kobulnicky, Salman Salman +14

Outcomes in stem cell transplantation (SCT) are modeled using probability theory. However the clinical course following SCT appears to demonstrate many characteristics of dynamical…