output
20112026
most citedDirect-coupling analysis of residue co-evolution captures native contacts across many protein families

1.6k citations

Showing 2014Show all

5 papers · 1 filter

q-bio.CB2014★ 105 cited

Individuality and universality in the growth-division laws of single E. coli cells

Andrew S. Kennard, Matteo Osella, Avelino Javer +5

The mean size of exponentially dividing E. coli cells cultured in different nutrient conditions is known to depend on the mean growth rate only. However, the joint fluctuations rel…

cond-mat.stat-mech2014★ 3 cited

Soft bounds on diffusion produce skewed distributions and Gompertz growth

Salvatore Mandrà, Marco Cosentino Lagomarsino, Marco Gherardi

Constraints can affect dramatically the behavior of diffusion processes. Recently, we analyzed a natural and a technological system and reported that they perform diffusion-like di…

cond-mat.soft2014

Combined collapse by bridging and self-adhesion in a prototypical polymer model inspired by the bacterial nucleoid

Vittore F. Scolari, Marco Cosentino Lagomarsino

Recent experimental results suggest that the E. coli chromosome feels a self-attracting interaction of osmotic origin, and is condensed in foci by bridging interactions. Motivated…

q-bio.QM2014★ 29 cited

Large Pseudo-Counts and -Norm Penalties Are Necessary for the Mean-Field Inference of Ising and Potts Models

J. P. Barton, S. Cocco, E. De Leonardis +1

Mean field (MF) approximation offers a simple, fast way to infer direct interactions between elements in a network of correlated variables, a common, computationally challenging pr…

q-bio.QM2014★ 158 cited

Fast and accurate multivariate Gaussian modeling of protein families: Predicting residue contacts and protein-interaction partners

Carlo Baldassi, Marco Zamparo, Christoph Feinauer +4

In the course of evolution, proteins show a remarkable conservation of their three-dimensional structure and their biological function, leading to strong evolutionary constraints o…