315 citations · 1k across the 10 of their papers we have counts for
10 papers
How pairwise coevolutionary models capture the collective residue variability in proteins
Matteo Figliuzzi, Pierre Barrat-Charlaix, Martin Weigt
Global coevolutionary models of homologous protein families, as constructed by direct coupling analysis (DCA), have recently gained popularity in particular due to their capacity t…
Inverse Statistical Physics of Protein Sequences: A Key Issues Review
Simona Cocco, Christoph Feinauer, Matteo Figliuzzi +2
In the course of evolution, proteins undergo important changes in their amino acid sequences, while their three-dimensional folded structure and their biological function remain re…
Improving landscape inference by integrating heterogeneous data in the inverse Ising problem
Pierre Barrat-Charlaix, Matteo Figliuzzi, Martin Weigt
The inverse Ising problem and its generalizations to Potts and continuous spin models have recently attracted much attention thanks to their successful applications in the statisti…
Probing the limits to microRNA-mediated control of gene expression
Araks Martirosyan, Matteo Figliuzzi, Enzo Marinari +1
According to the `ceRNA hypothesis', microRNAs (miRNAs) may act as mediators of an effective positive interaction between long coding or non-coding RNA molecules, carrying signific…
Coevolutionary landscape inference and the context-dependence of mutations in beta-lactamase TEM-1
Matteo Figliuzzi, Hervé Jacquier, Alexander Schug +2
The quantitative characterization of mutational landscapes is a task of outstanding importance in evolutionary and medical biology: It is, e.g., of central importance for our under…
RNA-based regulation: dynamics and response to perturbations of competing RNAs
Matteo Figliuzzi, Andrea De Martino, Enzo Marinari
The observation that, through a titration mechanism, microRNAs (miRNAs) can act as mediators of effective interactions among their common targets (competing endogenous RNAs or ceRN…