315 citations · 1k across the 10 of their papers we have counts for
5 papers · 1 filter
Probing the limits to microRNA-mediated control of gene expression
Araks Martirosyan, Matteo Figliuzzi, Enzo Marinari +1
According to the `ceRNA hypothesis', microRNAs (miRNAs) may act as mediators of an effective positive interaction between long coding or non-coding RNA molecules, carrying signific…
RNA-based regulation: dynamics and response to perturbations of competing RNAs
Matteo Figliuzzi, Andrea De Martino, Enzo Marinari
The observation that, through a titration mechanism, microRNAs (miRNAs) can act as mediators of effective interactions among their common targets (competing endogenous RNAs or ceRN…
MicroRNAs as a selective channel of communication between competing RNAs: a steady-state theory
Matteo Figliuzzi, Enzo Marinari, Andrea De Martino
It has recently been suggested that the competition for a finite pool of microRNAs (miRNA) gives rise to effective interactions among their common targets (competing endogenous RNA…
A scalable algorithm to explore the Gibbs energy landscape of genome-scale metabolic networks
Daniele De Martino, Matteo Figliuzzi, Andrea De Martino +1
The integration of various types of genomic data into predictive models of biological networks is one of the main challenges currently faced by computational biology. Constraint-ba…
Computing fluxes and chemical potential distributions in biochemical networks: energy balance analysis of the human red blood cell
Daniele De Martino, Matteo Figliuzzi, Andrea De Martino +1
The analysis of non-equilibrium steady states of biochemical reaction networks relies on finding the configurations of fluxes and chemical potentials satisfying stoichiometric (mas…