491 citations · 3.8k across the 67 of their papers we have counts for
68 papers
State- versus Reaction-Based Information Processing in Biochemical Networks
Anne-Lena Moor, Age Tjalma, Manuel Reinhardt +2
Trajectory mutual information is frequently used to quantify information transfer in biochemical systems. Tractable solutions of the trajectory mutual information can be obtained v…
Predicting concentration changes via discrete sampling
Age J. Tjalma, Pieter Rein ten Wolde
To successfully navigate chemical gradients, microorganisms need to predict how the ligand concentration changes in space. Due to their limited size, they do not take a spatial der…
Exploiting bias in optimal finite-time copying protocols
Daan Mulder, Pieter Rein ten Wolde, Thomas E. Ouldridge
We study a finite-time cyclic copy protocol that creates persisting correlations between a memory and a data bit. The average work to copy the two states of the data bit consists o…
Predicting a noisy signal: the costs and benefits of time averaging as a noise mitigation strategy
Jenny Poulton, Age Tjalma, Lotte Slim +1
One major challenge for living cells is the measurement and prediction of signals corrupted by noise. In general, cells need to make decisions based on their compressed representat…
Stable developmental patterns of gene expression without morphogen gradients
Maciej Majka, Nils B. Becker, Pieter Rein ten Wolde +2
Gene expression patterns (GEPs) are established by cross-regulating target genes that interpret morphogen gradients. However, as development progresses, morphogen activity is reduc…
Synchronous replication initiation of multiple origins
Mareike Berger, Pieter Rein ten Wolde
Initiating replication synchronously at multiple origins of replication allows the bacterium Escherichia coli to divide even faster than the time it takes to replicate the entire c…