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q-bio.QM2008★ 24 cited
Statistical properties of multistep enzyme-mediated reactions
Wiet H. de Ronde, Bryan C. Daniels, Andrew Mugler +2
Enzyme-mediated reactions may proceed through multiple intermediate conformational states before creating a final product molecule, and one often wishes to identify such intermedia…
q-bio.MN2008★ 1 cited
Coarse-graining stochastic biochemical networks: quasi-stationary approximation and fast simulations using a stochastic path integral technique
N. A. Sinitsyn, Nicolas Hengartner, Ilya Nemenman
We propose a universal approach for analysis and fast simulations of stiff stochastic biochemical kinetics networks, which rests on elimination of fast chemical species without a l…