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Neural coding of a natural stimulus ensemble: Uncovering information at sub-millisecond resolution
Ilya Nemenman, Geoffrey D. Lewen, William Bialek +1
Our knowledge of the sensory world is encoded by neurons in sequences of discrete, identical pulses termed action potentials or spikes. There is persistent controversy about the ex…
Optimal signal processing in small stochastic biochemical networks
Etay Ziv, Ilya Nemenman, Chris H. Wiggins
We quantify the influence of the topology of a transcriptional regulatory network on its ability to process environmental signals. By posing the problem in terms of information the…
The Berry phase and the pump flux in stochastic chemical kinetics
N. A. Sinitsyn, Ilya Nemenman
We study a classical two-state stochastic system in a sea of substrates and products (absorbing states), which can be interpreted as a single Michaelis-Menten catalyzing enzyme or…