activity
20002010
most citedARACNE: An Algorithm for the Reconstruction of Gene Regulatory Networks in a Mammalian Cellular Context

2.5k citations · 2.7k across the 13 of their papers we have counts for

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Showing 2004Show all

5 papers · 1 filter

q-bio.MN2004

Conditional Network Analysis Identifies Candidate Regulator Genes in Human B Cells

Kai Wang, Nilanjana Banerjee, Adam Margolin +4

Cellular phenotypes are determined by the dynamical activity of networks of co-regulated genes. Elucidating such networks is crucial for the understanding of normal cell physiology…

q-bio.MN20042.5k cited

ARACNE: An Algorithm for the Reconstruction of Gene Regulatory Networks in a Mammalian Cellular Context

Adam A. Margolin, Ilya Nemenman, Katia Basso +5

Background: Elucidating gene regulatory networks is crucial for understanding normal cell physiology and complex pathologic phenotypes. Existing computational methods for the genom…

q-bio.MN20046 cited

On The Reconstruction of Interaction Networks with Applications to Transcriptional Regulation

Adam A. Margolin, Ilya Nemenman, Chris Wiggins +2

A novel information-theoretic method for reconstruction of interaction networks is introduced. We prove that the method is exact for some class of networks. Performance tests on la…

q-bio.QM2004

Information theory, multivariate dependence, and genetic network inference

Ilya Nemenman

We define the concept of dependence among multiple variables using maximum entropy techniques and introduce a graphical notation to denote the dependencies. Direct inference of inf…

q-bio.NC2004

Fluctuation-dissipation theorem and models of learning

Ilya Nemenman

Advances in statistical learning theory have resulted in a multitude of different designs of learning machines. But which ones are implemented by brains and other biological inform…