activity
19942021
most citedTug-of-war as a cooperative mechanism for bidirectional cargo transport by molecular motors

538 citations · 3.1k across the 53 of their papers we have counts for

collaborators

53 papers

physics.bio-ph2021★ 7 cited

Biohybrid active matter -- the emergent properties of cell-mediated microtransport

Valentino Lepro, Robert Großmann, Oliver Nagel +4

As society paves its way towards device miniaturization and precision medicine, micro-scale actuation and guided transport become increasingly prominent research fields with high i…

physics.bio-ph2018★ 19 cited

Force-dependent unbinding rate of molecular motors from stationary optical trap data

Florian Berger, Stefan Klumpp, Reinhard Lipowsky

Molecular motors walk along filaments until they detach stochastically with a force-dependent unbinding rate. Here, we show that this unbinding rate can be obtained from the analys…

q-bio.BM2016★ 34 cited

Binding equilibrium and kinetics of membrane-anchored receptors and ligands in cell adhesion: insights from computational model systems and theory

Thomas R. Weikl, Jinglei Hu, Guang-Kui Xu +1

The adhesion of cell membranes is mediated by the binding of membrane-anchored receptor and ligand proteins. In this article, we review recent results from simulations and theory t…

q-bio.BM2015★ 41 cited

Binding kinetics of membrane-anchored receptors and ligands: molecular dynamics simulations and theory

Jinglei Hu, Guang-Kui Xu, Reinhard Lipowsky +1

The adhesion of biological membranes is mediated by the binding of membrane-anchored receptor and ligand proteins. Central questions are how the binding kinetics of these proteins…

q-bio.BM2015★ 65 cited

Binding constants of membrane-anchored receptors and ligands: a general theory corroborated by Monte Carlo simulations

Guang-Kui Xu, Jinglei Hu, Reinhard Lipowsky +1

Adhesion processes of biological membranes that enclose cells and cellular organelles are essential for immune responses, tissue formation, and signaling. These processes depend se…

q-bio.SC2015

The role of membrane curvature for the wrapping of nanoparticles

Amir Houshang Bahrami, Reinhard Lipowsky, Thomas R. Weikl

Cellular internalization of nanoparticles requires the full wrapping of the nanoparticles by the cell membrane. This wrapping process can occur spontaneously if the adhesive intera…