activity
19942021
most citedTug-of-war as a cooperative mechanism for bidirectional cargo transport by molecular motors

538 citations · 3.1k across the 53 of their papers we have counts for

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7 papers · 1 filter

q-bio.SC2015

The role of membrane curvature for the wrapping of nanoparticles

Amir Houshang Bahrami, Reinhard Lipowsky, Thomas R. Weikl

Cellular internalization of nanoparticles requires the full wrapping of the nanoparticles by the cell membrane. This wrapping process can occur spontaneously if the adhesive intera…

q-bio.SC2009★ 58 cited

Stochastic simulations of cargo transport by processive molecular motors

Christian B. Korn, Stefan Klumpp, Reinhard Lipowsky +1

We use stochastic computer simulations to study the transport of a spherical cargo particle along a microtubule-like track on a planar substrate by several kinesin-like processive…

q-bio.SC2008★ 538 cited

Tug-of-war as a cooperative mechanism for bidirectional cargo transport by molecular motors

Melanie J. I. Müller, Stefan Klumpp, Reinhard Lipowsky

Intracellular transport is based on molecular motors that pull cargos along cytoskeletal filaments. One motor species always moves in one direction, e.g. conventional kinesin moves…

q-bio.SC2006★ 4 cited

Cooperative transport by small teams of molecular motors

Stefan Klumpp, Melanie J. I. Muller, Reinhard Lipowsky

Molecular motors power directed transport of cargoes within cells. Even if a single motor is sufficient to transport a cargo, motors often cooperate in small teams. We discuss the…

q-bio.SC2005★ 406 cited

Cooperative Cargo Transport by Several Molecular Motors

Stefan Klumpp, Reinhard Lipowsky

The transport of cargo particles which are pulled by several molecular motors in a cooperative manner is studied theoretically. The transport properties depend primarily on the max…

q-bio.SC2005★ 66 cited

Self-organized density patterns of molecular motors in arrays of cytoskeletal filaments

Stefan Klumpp, Theo M. Nieuwenhuizen, Reinhard Lipowsky

The stationary states of systems with many molecular motors are studied theoretically for uniaxial and centered (aster-like) arrangements of cytoskeletal filaments using Monte Carl…