70 citations · 346 across the 43 of their papers we have counts for
8 papers · 1 filter
Universal Transitions between Growth and Dormancy via Intermediate Complex Formation
Jumpei F. Yamagishi, Kunihiko Kaneko
A simple cell model consisting of a catalytic reaction network with intermediate complex formation is numerically studied. As nutrients are depleted, the transition from the expone…
Molecular Diversity and Network Complexity in Growing Protocells
Atsushi Kamimura, Kunihiko Kaneko
A great variety of molecular components is encapsulated in cells. Each of these components is replicated for cell reproduction. To address an essential role of the huge diversity o…
Horizontal transfer between loose compartments stabilizes replication of fragmented ribozymes
Atsushi Kamimura, Yoshiya J. Matsubara, Kunihiko Kaneko +1
The emergence of replicases that can replicate themselves is a central issue in the origin of life. Recent experiments suggest that such replicases can be realized if an RNA polyme…
Exponential growth for self-reproduction in a catalytic reaction network: relevance of a minority molecular species and crowdedness
Atsushi Kamimura, Kunihiko Kaneko
Explanation of exponential growth in self-reproduction is an important step toward elucidation of the origins of life because optimization of the growth potential across rounds of…
Consistency Principle in Biological Dynamical Systems
Kunihiko Kaneko, Chikara Furusawa
We propose a principle of consistency between different hierarchical levels of biological systems. Given a consistency between molecule replication and cell reproduction, universal…
Regulative Differentiation as Bifurcation of Interacting Cell Population
Akihiko Nakajima, Kunihiko Kaneko
In multicellular organisms, several cell states coexist. For determining each cell type, cell-cell interactions are often essential, in addition to intracellular gene expression dy…