Exponential growth for self-reproduction in a catalytic reaction network: relevance of a minority molecular species and crowdedness
arXiv:1711.08988 · doi:10.1088/1367-2630/aaaf37
Abstract
Explanation of exponential growth in self-reproduction is an important step toward elucidation of the origins of life because optimization of the growth potential across rounds of selection is necessary for Darwinian evolution. To produce another copy with approximately the same composition, the exponential growth rates for all components have to be equal. How such balanced growth is achieved, however, is not a trivial question, because this kind of growth requires orchestrated replication of the components in stochastic and nonlinear catalytic reactions. By considering a mutually catalyzing reaction in two- and three-dimensional lattices, as represented by a cellular automaton model, we show that self-reproduction with exponential growth is possible only when the replication and degradation of one molecular species is much slower than those of the others, i.e., when there is a minority molecule. Here, the synergetic effect of molecular discreteness and crowding is necessary to produce the exponential growth. Otherwise, the growth curves show superexponential growth because of nonlinearity of the catalytic reactions or subexponential growth due to replication inhibition by overcrowding of molecules. Our study emphasizes that the minority molecular species in a catalytic reaction network is necessary to acquire evolvability at the primitive stage of life.
arXiv comment19 pages, submitted for publication
References in corpus (8)
- Zipf's Law in Gene Expression
- The Importance of Being Discrete - Life Always Wins on the Surface
- Transitions Induced by the Discreteness of Molecules in a Small Autocatalytic System
- Large extinctions in an evolutionary model: The role of innovation and keystone species
- Adaptation of Autocatalytic Fluctuations to Diffusive Noise
- Reproduction of a Protocell by Replication of Minority Molecule in Catalytic Reaction Network
- Discreteness-induced Stochastic Steady State in Reaction Diffusion Systems: Self-consistent Analysis and Stochastic Simulations
- Inverse Relationship Between Molecular Diversity And Resource Abundances