activity
20162026
most citedChanges in lipid membranes may trigger amyloid toxicity in Alzheimer's disease

105 citations · 120 across the 9 of their papers we have counts for

collaborators

12 papers

cond-mat.soft2026

Drying kinematics selects open honeycomb fold networks on solvent-extracted viscoelastic thin films and gels

Fan Zhao, Surjyasish Mitra, Sunandan Tandon +3

Solvent extraction and drying of substrate-supported viscoelastic films and gels produce quasiperiodic networks of three-armed surface folds. In this Letter, we examine the physica…

physics.bio-ph2024★ 7 cited

Protective Effect of Trehalose Sugar on Amyloid-Membrane Interactions using BLM Electrophysiology

Yue Xu, Carina Teresa Filice, Zoya Leonenko

Alzheimer's disease (AD) is a neurodegenerative disease characterized by dementia and memory loss in the elderly population. The amyloid- peptide (A 1-42) is one of the main…

physics.bio-ph2017★ 105 cited

Changes in lipid membranes may trigger amyloid toxicity in Alzheimer's disease

Elizabeth Drolle, Alexander Negoda, Keely Hammond +2

Amyloid beta peptides (A\b{eta}), implicated in Alzheimers disease (AD), interact with the cellular membrane and induce amyloid toxicity. The composition of cellular membranes chan…

q-bio.CB2017

Novel Nongenomic Signaling by Glucocorticoid May Involve Changes to Liver Membrane Order in Rainbow Trout

L Dindia, J Murray, Erin Faught +3

Stress-induced glucocorticoid elevation is a highly conserved response among vertebrates. This facilitates stress adaptation and the mode of action involves activation of the intra…

physics.bio-ph2017

AFM-Assisted Fabrication of Thiol SAM Pattern with Alternating Quantified Surface Potential

Brad Moores, Janet Simons, S Xu +1

Thiol self assembled monolayers (SAMs) are widely used in many nano- and bio-technology applications. We report a new approach to create and characterize a thiol SAMs micropattern…

physics.bio-ph2017

Effect of Surfaces on Amyloid Fibril Formation

Brad Moores, Elizabeth Drolle, Simon Attwood +2

Using atomic force microscopy (AFM) we investigated the interaction of amyloid beta (Ab) (1 42) peptide with chemically modified surfaces in order to better understand the mechanis…

physics.bio-ph2017★ 2 cited

Cu2+ Affects Amyloid-\b{eta} (1-42) Aggregation by Increasing Peptide-Peptide Binding Forces

Francis Hane, Gary Tran, Simon Attwood +1

The link between metals, Alzheimers disease (AD) and its implicated protein, amyloid \b{eta} (A\b{eta}), is complex and highly studied. AD is believed to occur as a result of the m…

physics.bio-ph2017

Magnetic Force Microscopy Characterization of Superparamagnetic Iron Oxide Nanoparticles (SPIONs)

Gustavo Cordova, Simon Attwood, Ravi Gaikwad +2

Superparamagnetic iron oxide nanoparticles (SPIONs), due to their controllable sizes, relatively long in vivo half-life and limited agglomeration, are ideal for biomedical applicat…

physics.bio-ph2017

Effect of Metals on Kinetic Pathways of Amyloid-\b{eta} Aggregation

Francis Hane, Zoya Leonenko

Metal ions, including copper and zinc, have been implicated in the pathogenesis of Alzheimers disease through a variety of mechanisms including increased amyloid \b{eta} affinity a…

physics.bio-ph2017★ 5 cited

Drugs and Drug Delivery Systems Targeting Amyloid-\b{eta} in Alzheimers Disease

Morgan Robinson, Brenda Yasie Lee, Zoya Leonenko

Alzheimer's disease (AD) is a devastating neurodegenerative disorder with no cure and limited treatment solutions that are unable to target any of the suspected causes. Increasing…

physics.ins-det2017

Magnetic Force Microscopy for Nanoparticle Characterization

Gustavo Cordova, Brenda Yasie Lee, Zoya Leonenko

Since the invention of the atomic force microscope (AFM) in 1986, there has been a drive to apply this scanning probe technique or a form of this technique to various disciplines i…

cond-mat.soft2016★ 1 cited

Molecular Dynamics simulations and Kelvin Probe Force microscopy to study of cholesterol-induced electrostatic nanodomains in complex lipid mixtures

Elizabeth Drolle, W. F. D. Bennett, K. Hammond +3

The molecular arrangement of lipids and proteins within biomembranes and monolayers gives rise to complex film morphologies as well as regions of distinct electrical surface potent…