105 citations · 120 across the 9 of their papers we have counts for
9 papers · 1 filter
Changes in lipid membranes may trigger amyloid toxicity in Alzheimer's disease
Elizabeth Drolle, Alexander Negoda, Keely Hammond +2
Amyloid beta peptides (A\b{eta}), implicated in Alzheimers disease (AD), interact with the cellular membrane and induce amyloid toxicity. The composition of cellular membranes chan…
Novel Nongenomic Signaling by Glucocorticoid May Involve Changes to Liver Membrane Order in Rainbow Trout
L Dindia, J Murray, Erin Faught +3
Stress-induced glucocorticoid elevation is a highly conserved response among vertebrates. This facilitates stress adaptation and the mode of action involves activation of the intra…
AFM-Assisted Fabrication of Thiol SAM Pattern with Alternating Quantified Surface Potential
Brad Moores, Janet Simons, S Xu +1
Thiol self assembled monolayers (SAMs) are widely used in many nano- and bio-technology applications. We report a new approach to create and characterize a thiol SAMs micropattern…
Effect of Surfaces on Amyloid Fibril Formation
Brad Moores, Elizabeth Drolle, Simon Attwood +2
Using atomic force microscopy (AFM) we investigated the interaction of amyloid beta (Ab) (1 42) peptide with chemically modified surfaces in order to better understand the mechanis…
Cu2+ Affects Amyloid-\b{eta} (1-42) Aggregation by Increasing Peptide-Peptide Binding Forces
Francis Hane, Gary Tran, Simon Attwood +1
The link between metals, Alzheimers disease (AD) and its implicated protein, amyloid \b{eta} (A\b{eta}), is complex and highly studied. AD is believed to occur as a result of the m…
Magnetic Force Microscopy Characterization of Superparamagnetic Iron Oxide Nanoparticles (SPIONs)
Gustavo Cordova, Simon Attwood, Ravi Gaikwad +2
Superparamagnetic iron oxide nanoparticles (SPIONs), due to their controllable sizes, relatively long in vivo half-life and limited agglomeration, are ideal for biomedical applicat…
Effect of Metals on Kinetic Pathways of Amyloid-\b{eta} Aggregation
Francis Hane, Zoya Leonenko
Metal ions, including copper and zinc, have been implicated in the pathogenesis of Alzheimers disease through a variety of mechanisms including increased amyloid \b{eta} affinity a…
Drugs and Drug Delivery Systems Targeting Amyloid-\b{eta} in Alzheimers Disease
Morgan Robinson, Brenda Yasie Lee, Zoya Leonenko
Alzheimer's disease (AD) is a devastating neurodegenerative disorder with no cure and limited treatment solutions that are unable to target any of the suspected causes. Increasing…
Magnetic Force Microscopy for Nanoparticle Characterization
Gustavo Cordova, Brenda Yasie Lee, Zoya Leonenko
Since the invention of the atomic force microscope (AFM) in 1986, there has been a drive to apply this scanning probe technique or a form of this technique to various disciplines i…