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physics.bio-ph2020
The role of mechanics in the growth and homeostasis of the intestinal crypt
Axel A. Almet, Helen M. Byrne, Philip K. Maini +1
We present a mechanical model of tissue homeostasis that is specialised to the intestinal crypt. Growth and deformation of the crypt, idealised as a line of cells on a substrate, a…
physics.bio-ph2016★ 6 cited
Optimisation of Simulations of Stochastic Processes by Removal of Opposing Reactions
Fabian Spill, Philip K. Maini, Helen Byrne
Models invoking the chemical master equation are used in many areas of science, and, hence, their simulation is of interest to many researchers. The complexity of the problems at h…