50 citations · 62 across the 3 of their papers we have counts for
3 papers
Investigating the influence of growth arrest mechanisms on tumour responses to radiotherapy
Chloé Colson, Philip K. Maini, Helen M. Byrne
Cancer is a heterogeneous disease and tumours of the same type can differ greatly at the genetic and phenotypic levels. Understanding how these differences impact sensitivity to tr…
3D hybrid modeling of vascular network formation
Holger Perfahl, Barry D Hughes, Tomas Alaracon +4
We develop an agent-based model of vasculogenesis, the de novo formation of blood vessels. Endothelial cells in the vessel network are viewed as linearly elastic spheres and are of…
Parameter-free methods distinguish Wnt pathway models and guide design of experiments
Adam L. MacLean, Zvi Rosen, Helen M. Byrne +1
The canonical Wnt signaling pathway, mediated by -catenin, is crucially involved in development, adult stem cell tissue maintenance and a host of diseases including cancer. We u…