Polymer translocation through a nanopore under a pulling force

Abstract

We investigate polymer translocation through a nanopore under a pulling force using Langevin dynamics simulations. We concentrate on the influence of the chain length $N$ and the pulling force $F$ on the translocation time $\tau$. The distribution of $\tau$ is symmetric and narrow for strong $F$. We find that $\tau \sim N^2$ and translocation velocity $v\sim N^{-1}$ for both moderate and strong $F$. For infinitely wide pores, three regimes are observed for $\tau$ as a function of $F$. With increasing $F$, $\tau$ is independent of $F$ for weak $F$, and then $\tau \sim F^{-2+{\nu }^{-1}}$ for moderate $F$, where $\nu$ is the Flory exponent, which finally crosses over to $\tau \sim F^{-1}$ for strong force. For narrow pores, even for moderate force $\tau \sim F^{-1}$. Finally, the waiting time, for monomer $s$ and monomer $s+1$ to exit the pore, has a maximum for $s$ close to the end of the chain, in contrast to the case where polymer is driven by an external force within the pore.

submitted, 7 pages with 5 figures. To appear in PRE

References in corpus (2)

• Langevin Dynamics Simulations of Polymer Translocation through Nanopores
• Heteropolymer translocation through nanopores

Cited by in corpus (11)

• Influence of polymer-pore interactions on translocation
• Sequence dependence of DNA translocation through a nanopore
• Dynamical Scaling Exponents for Polymer Translocation through a Nanopore
• Comment on ``Passage Times for Unbiased Polymer Translocation through a Narrow Pore''
• Passage Times for Polymer Translocation Pulled through a Narrow Pore
• Translocation Dynamics with Attractive Nanopore-Polymer Interactions
• Dynamics of DNA translocation through an attractive nanopore
• Probability distributions for polymer translocation
• Polymer translocation out of confined environments
• Noise driven translocation of short polymers in crowded solutions
• Resonance-like phenomena of the mobility of a chain of nonlinear coupled oscillators in a two-dimensional periodic potential