The chain sucker: translocation dynamics of a polymer chain into a long narrow channel driven by longitudinal flow

Abstract

Using analytical techniques and Langevin dynamics simulations, we investigate the dynamics of polymer translocation into a narrow channel of width $R$ embedded in two dimensions, driven by a force proportional to the number of monomers in the channel. Such a setup mimics typical experimental situations in nano/micro-fluidics. During the the translocation process if the monomers in the channel can sufficiently quickly assume steady state motion, we observe the scaling $\tau \sim N/F$ of the translocation time $\tau$ with the driving force $F$ per bead and the number $N$ of monomers per chain. With smaller channel width $R$, steady state motion cannot be achieved, effecting a non-universal dependence of $\tau$ on $N$ and $F$. From the simulations we also deduce the waiting time distributions under various conditions for the single segment passage through the channel entrance. For different chain lengths but the same driving force, the curves of the waiting time as a function of the translocation coordinate $s$ feature a maximum located at identical $s_{\max }$, while with increasing the driving force or the channel width the value of $s_{\max }$ decreases.

9 pages, 14 figures. To appear in J. Chem. Phys

References in corpus (17)

• Nonequilibrium dynamics of polymer translocation and straightening
• Influence of polymer-pore interactions on translocation
• Sequence dependence of DNA translocation through a nanopore
• Langevin Dynamics Simulations of Polymer Translocation through Nanopores
• Polymer translocation through a nanopore - a showcase of anomalous diffusion
• Driven polymer translocation through nanopores: slow versus fast dynamics
• Driven polymer translocation through a nanopore: a manifestation of anomalous diffusion
• Dynamical Scaling Exponents for Polymer Translocation through a Nanopore
• Comment on ``Passage Times for Unbiased Polymer Translocation through a Narrow Pore''
• Pore-blockade Times for Field-Driven Polymer Translocation
• Hydrodynamic correlations in the translocation of biopolymer through a nanopore: theory and multiscale simulations
• Polymer translocation through a nanopore under a pulling force
• Heteropolymer translocation through nanopores
• Out of Equilibrium Characteristics of a Forced Translocating Chain through a Nanopore
• Polymer translocation into a fluidic channel through a nanopore
• Translocation Dynamics with Attractive Nanopore-Polymer Interactions
• Dynamics of DNA translocation through an attractive nanopore

Cited by in corpus (8)

• Active polymer translocation through flickering pores
• Non-monotonous polymer translocation time across corrugated channels: comparison between Fick-Jacobs approximation and numerical simulations
• Polymer translocation into and out of an ellipsoidal cavity
• Driven polymer translocation through a cylindrical nanochannel: Interplay between the channel length and the chain length
• Polymer translocation into cavities: Effects of confinement geometry, crowding and bending rigidity on the free energy
• Dynamics of polymer translocation into a circular nanocontainer through a nanopore
• Easier sieving through narrower pores: fluctuations and barrier crossing in flow-driven polymer translocation
• Translocation of short and long polymers through an interacting pore