A quantum mechanical scheme to reduce radiation damage in electron microscopy
arXiv:1506.07215 · doi:10.1063/1.2191096
Abstract
We show that radiation damage to unstained biological specimens is not an intractable problem in electron microscopy. When a structural hypothesis of a specimen is available, quantum mechanical principles allow us to verify the hypothesis with a very low electron dose. Realization of such a concept requires precise control of the electron wave front. Based on a diffractive electron optical implementation, we demonstrate the feasibility of this new method by both experimental and numerical investigations.
8 pages, 3 figures