Efficient molecule discrimination in electron microcopy through an optimized orbital angular momentum sorter

Abstract

We consider the problem of discriminating macromolecular structures in an electron microscope, through a specific beam shaping technique. Our approach is based on maximizing the which-molecule information extracted from the state of each electron. To this aim, the optimal observables are derived within the framework of quantum state discrimination, which allows one to fully account from the quantum character of the probe. We simulate the implementation of such optimal observable on a generalized orbital angular momentum (OAM) sorter and benchmark its performance against the best known real space approach.

arXiv comment6 pages, 3 figures and 1 table

References in corpus (5)

• Quantum sensing
• Quantum state discrimination and its applications
• Efficient Sorting of Free Electron Orbital Angular Momentum
• Nondestructive Measurement of Orbital Angular Momentum for an Electron Beam
• A quantum mechanical scheme to reduce radiation damage in electron microscopy

Cited by in corpus (5)

• Experimental demonstration of an electrostatic orbital angular momentum sorter for electrons
• Entanglement of Orbital Angular Momentum in Non-Sequential Double Ionization
• Transmission Electron Microscopy at the Quantum Limit
• Quantum estimation and remote charge sensing with a hole-spin qubit in silicon
• Alignment of electron optical beam shaping elements using a convolutional neural network