503 citations
- Indiana University BloomingtonUS15 papers
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- Centre National de la Recherche ScientifiqueFR3 papers
- Coordenação de Aperfeicoamento de Pessoal de Nível SuperiorBR3 papers
- European Bioinformatics InstituteGB3 papers
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4 papers · 1 filter
Control of complex networks requires both structure and dynamics
Alexander J. Gates, Luis M. Rocha
The study of network structure has uncovered signatures of the organization of complex systems. However, there is also a need to understand how to control them; for example, identi…
SBML Qualitative Models: a model representation format and infrastructure to foster interactions between qualitative modelling formalisms and tools
Claudine Chaouiya, Duncan Berenguier, Sarah M Keating +21
Background: Qualitative frameworks, especially those based on the logical discrete formalism, are increasingly used to model regulatory and signalling networks. A major advantage o…
Large-scale generation of computational models from biochemical pathway maps
Finja Büchel, Nicolas Rodriguez, Neil Swainston +23
Background: Systems biology projects and omics technologies have led to a growing number of biochemical pathway reconstructions. However, mathematical models are still most often c…
Canalization and control in automata networks: body segmentation in Drosophila melanogaster
Manuel Marques-Pita, Luis M. Rocha
We present schema redescription as a methodology to characterize canalization in automata networks used to model biochemical regulation and signalling. In our formulation, canaliza…