output
20132024
most citedPili mediated intercellular forces shape heterogeneous bacterial microcolonies prior to multicellular differentiation

47 citations

6 papers

q-bio.QM2024★ 32 cited

The Rise of Data-Driven Microscopy powered by Machine Learning

Leonor Morgado, Estibaliz Gómez-de-Mariscal, Hannah S. Heil +1

Optical microscopy is an indispensable tool in life sciences research, but conventional techniques require compromises between imaging parameters like speed, resolution, field-of-v…

q-bio.QM2023★ 20 cited

Harnessing Artificial Intelligence To Reduce Phototoxicity in Live Imaging

Estibaliz Gómez-de-Mariscal, Mario Del Rosario, Joanna W Pylvänäinen +2

Fluorescence microscopy, widely used in the study of living cells, tissues, and organisms, often faces the challenge of photodamage. This is primarily caused by the interaction bet…

q-bio.QM2022★ 16 cited

Mapping molecular complexes with Super-Resolution Microscopy and Single-Particle Analysis

Afonso Mendes, Hannah S. Heil, Simao Coelho +2

Understanding the structure of supramolecular complexes provides insight into their functional capabilities and how they can be modulated in the context of disease. Super-resolutio…

physics.bio-ph2018★ 13 cited

How bacterial cells and colonies move on solid substrates

Wolfram Pönisch, Christoph A. Weber, Vasily Zaburdaev

Many bacteria rely on active cell appendages, such as type IV pili, to move over substrates and interact with neighboring cells. Here, we study the motion of individual cells and b…

physics.bio-ph2017★ 47 cited

Pili mediated intercellular forces shape heterogeneous bacterial microcolonies prior to multicellular differentiation

Wolfram Pönisch, Kelly Eckenrode, Khaled Alzurqa +4

Microcolonies are aggregates of a few dozen to a few thousand cells exhibited by many bacteria. The formation of microcolonies is a crucial step towards the formation of more matur…

q-bio.TO2013★ 21 cited

Cooperation and competition in the dynamics of tissue architecture during homeostasis and tumorigenesis

Attila Csikász-Nagy, Luis M. Escudero, Martial Guillaud +3

The construction of a network of cell-to-cell contacts makes it possible to characterize the patterns and spatial organisation of tissues. Such networks are highly dynamic, dependi…