activity
20132024
most citedLarge-scale generation of computational models from biochemical pathway maps

185 citations · 207 across the 6 of their papers we have counts for

collaborators

6 papers

cs.DM2024

Computation of Immediate Neighbours of Monotone Boolean Functions

José E. R. Cury, Patrícia Tenera Roxo, Vasco Manquinho +2

Boolean networks constitute relevant mathematical models to study the behaviours of genetic and signalling networks. These networks define regulatory influences between molecular n…

cs.DM2019★ 6 cited

Partial Order on the set of Boolean Regulatory Functions

José E. R. Cury, Pedro T. Monteiro, Claudine Chaouiya

Logical models have been successfully used to describe regulatory and signaling networks without requiring quantitative data. However, existing data is insufficient to adequately d…

cs.DM2018★ 3 cited

Local negative circuits and cyclic attractors in Boolean networks with at most five components

Elisa Tonello, Etienne Farcot, Claudine Chaouiya

We consider the following question on the relationship between the asymptotic behaviours of asynchronous dynamics of Boolean networks and their regulatory structures: does the pres…

cs.DM2014★ 8 cited

Quantification of reachable attractors in asynchronous discrete dynamics

Nuno D. Mendes, Pedro T. Monteiro, Jorge Carneiro +2

Motivation: Models of discrete concurrent systems often lead to huge and complex state transition graphs that represent their dynamics. This makes difficult to analyse dynamical pr…

q-bio.MN2013★ 5 cited

SBML Qualitative Models: a model representation format and infrastructure to foster interactions between qualitative modelling formalisms and tools

Claudine Chaouiya, Duncan Berenguier, Sarah M Keating +21

Background: Qualitative frameworks, especially those based on the logical discrete formalism, are increasingly used to model regulatory and signalling networks. A major advantage o…

q-bio.MN2013★ 185 cited

Large-scale generation of computational models from biochemical pathway maps

Finja Büchel, Nicolas Rodriguez, Neil Swainston +23

Background: Systems biology projects and omics technologies have led to a growing number of biochemical pathway reconstructions. However, mathematical models are still most often c…