59 citations
- Fred Hutch Cancer CenterUS9 papers
- Cape Town HVTN Immunology Laboratory / Hutchinson Centre Research Institute of South AfricaZA5 papers
- University of WashingtonUS5 papers
- Columbia UniversityUS2 papers
- University of Hawaiʻi at MānoaUS2 papers
- Brigham and Women's HospitalUS1 paper
- California Institute of TechnologyUS1 paper
- Cancer Center of HawaiiUS1 paper
- Comprehensive Cancer Center ErlangenDE1 paper
- Dartmouth CollegeUS1 paper
- École Normale Supérieure - PSLFR1 paper
- Fraunhofer Institute for Digital MedicineDE1 paper
12 papers
From Data to Diagnosis: A Large, Comprehensive Bone Marrow Dataset and AI Methods for Childhood Leukemia Prediction
Henning Höfener, Farina Kock, Martina Pontones +9
Leukemia diagnosis primarily relies on manual microscopic analysis of bone marrow morphology supported by additional laboratory parameters, making it complex and time consuming. Wh…
Generalized Data Thinning Using Sufficient Statistics
Ameer Dharamshi, Anna Neufeld, Keshav Motwani +3
Our goal is to develop a general strategy to decompose a random variable into multiple independent random variables, without sacrificing any information about unknown parameter…
MINIMALIST: Mutual INformatIon Maximization for Amortized Likelihood Inference from Sampled Trajectories
Giulio Isacchini, Natanael Spisak, Armita Nourmohammad +2
Simulation-based inference enables learning the parameters of a model even when its likelihood cannot be computed in practice. One class of methods uses data simulated with differe…
An Approximate Quasi-Likelihood Approach for Error-Prone Failure Time Outcomes and Exposures
Lillian A. Boe, Lesley F. Tinker, Pamela A. Shaw
Measurement error arises commonly in clinical research settings that rely on data from electronic health records or large observational cohorts. In particular, self-reported outcom…
Estimands and Inference in Cluster-Randomized Vaccine Trials
Kayla W. Kilpatrick, Michael G. Hudgens, M. Elizabeth Halloran
Cluster-randomized trials are often conducted to assess vaccine effects. Defining estimands of interest before conducting a trial is integral to the alignment between a study's obj…
Estimation of cell lineage trees by maximum-likelihood phylogenetics
Jean Feng, William S DeWitt, Aaron McKenna +3
CRISPR technology has enabled large-scale cell lineage tracing for complex multicellular organisms by mutating synthetic genomic barcodes during organismal development. However, th…