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4 papers
Humanity's Last Exam
Long Phan, Alice Gatti, Ziwen Han +1144
Benchmarks are important tools for tracking the rapid advancements in large language model (LLM) capabilities. However, benchmarks are not keeping pace in difficulty: LLMs now achi…
Ultra-Sharp Nanowire Arrays Natively Permeate, Record, and Stimulate Intracellular Activity in Neuronal and Cardiac Networks
Ren Liu, Jihwan Lee, Youngbin Tchoe +16
Intracellular access with high spatiotemporal resolution can enhance our understanding of how neurons or cardiomyocytes regulate and orchestrate network activity, and how this acti…
Systems approaches and algorithms for discovery of combinatorial therapies
Jacob D. Feala, Jorge Cortes, Phillip M. Duxbury +3
Effective therapy of complex diseases requires control of highly non-linear complex networks that remain incompletely characterized. In particular, drug intervention can be seen as…
Metabolomic and flux-balance analysis of age-related decline of hypoxia tolerance in Drosophila muscle tissue
Laurence Coquin, Jacob D. Feala, Andrew D. McCulloch +1
The fruit fly D. melanogaster is increasingly used as a model organism for studying acute hypoxia tolerance and for studying aging, but the interactions between these two factors a…