output
20072023
most citedA general framework for modeling tumor-immune system competition and immunotherapy: mathematical analysis and biomedical inferences

296 citations

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q-bio.TO2013★ 296 cited

A general framework for modeling tumor-immune system competition and immunotherapy: mathematical analysis and biomedical inferences

Alberto d'Onofrio

In this work we propose and investigate a family of models, which admits as particular cases some well known mathematical models of tumor-immune system interaction, with the additi…

q-bio.TO2013★ 70 cited

A non-linear mathematical model of cell turnover, differentiation and tumorigenesis in the intestinal crypt

Alberto d'Onofrio, Ian P. M. Tomlinson

We present a development of a model of the relationship between cells in three compartments of the intestinal crypt: stem cells, semi-differentiated cells and fully differentiated…

q-bio.TO2013★ 38 cited

Fractal growth of tumors and other cellular populations: Linking the mechanistic to the phenomenological modeling and vice versa

Alberto d'Onofrio

In this paper we study and extend the mechanistic mean field theory of growth of cellular populations proposed by Mombach et al in (Mombach J. C. M. et al., Europhysics Letter, 59…