27 citations
Counting papers with at most 25 authors, so collaboration author lists do not stand in for the people here.
- Université de BordeauxFR7 papers
- Bordeaux Population HealthFR6 papers
- Centre Hospitalier Universitaire de BordeauxFR3 papers
- Harvard UniversityUS3 papers
- InsermFR3 papers
- Institut national de recherche en sciences et technologies du numériqueFR3 papers
- SISTM: Statistics In System biology and Translational MedicineFR3 papers
- RAND CorporationUS2 papers
- The University of Texas at AustinUS2 papers
- Boston Children's HospitalUS1 paper
- Brigham and Women's HospitalUS1 paper
- Brown UniversityUS1 paper
8 papers
Representation learning to advance multi-institutional studies with electronic health record data from US and France
Doudou Zhou, Han Tong, Linshanshan Wang +21
The widespread adoption of electronic health records has created new opportunities for translational clinical research, yet this promise remains constrained by fragmented data acro…
RISE: Two-Stage Rank-Based Identification of High-Dimensional Surrogate Markers Applied to Vaccinology
Arthur Hughes, Layla Parast, Rodolphe Thiébaut +1
In vaccine trials with long-term participant follow-up, it is of great importance to identify surrogate markers that accurately infer long-term immune responses. These markers offe…
Practical limitations for real-life application of data fission and data thinning in post-clustering differential analysis
Benjamin Hivert, Denis Agniel, Rodolphe Thiébaut +1
Post-clustering inference in single-cell RNA sequencing (scRNA-seq) analysis presents significant challenges in controlling Type I error during differential expression analysis. Da…
Doubly-robust evaluation of high-dimensional surrogate markers
Denis Agniel, Layla Parast, Boris Hejblum
When evaluating the effectiveness of a treatment, policy, or intervention, the desired measure of effectiveness may be expensive to collect, not routinely available, or may take a…
EpidemiOptim: A Toolbox for the Optimization of Control Policies in Epidemiological Models
Cédric Colas, Boris Hejblum, Sébastien Rouillon +4
Epidemiologists model the dynamics of epidemics in order to propose control strategies based on pharmaceutical and non-pharmaceutical interventions (contact limitation, lock down,…
Sequential Dirichlet Process Mixtures of Multivariate Skew t-distributions for Model-based Clustering of Flow Cytometry Data
Boris P. Hejblum, Chariff Alkhassim, Raphael Gottardo +2
Flow cytometry is a high-throughput technology used to quantify multiple surface and intracellular markers at the level of a single cell. This enables to identify cell sub-types, a…
Variance component score test for time-course gene set analysis of longitudinal RNA-seq data
Denis Agniel, Boris P Hejblum
As gene expression measurement technology is shifting from microarrays to sequencing, the statistical tools available for their analysis must be adapted since RNA-seq data are meas…
Modeling CD4+ T cells dynamics in HIV-infected patients receiving repeated cycles of exogenous Interleukin 7
Ana Jarne, Daniel Commenges, Mélanie Prague +2
Combination Antiretroviral Therapy (cART) succeeds to control viral replication in most HIV infected patients. This is normally followed by a reconstitution of the CD4 T cells…