106 citations · 115 across the 6 of their papers we have counts for
8 papers
Doubly-robust evaluation of high-dimensional surrogate markers
Denis Agniel, Layla Parast, Boris Hejblum
When evaluating the effectiveness of a treatment, policy, or intervention, the desired measure of effectiveness may be expensive to collect, not routinely available, or may take a…
Supervised Learning for Multi-Block Incomplete Data
Hadrien Lorenzo, Jérôme Saracco, Rodolphe Thiébaut
In the supervised high dimensional settings with a large number of variables and a low number of individuals, one objective is to select the relevant variables and thus to reduce t…
Controlling IL-7 injections in HIV-infected patients
Chloé Pasin, François Dufour, Laura Villain +2
Immune interventions consisting in repeated injection are broadly used as they are thought to improve the quantity and the quality of the immune response. However, they also raised…
Dynamic models for estimating the effect of HAART on CD4 in observational studies: application to the Aquitaine Cohort study and the Swiss HIV Cohort Study
M. Prague, D. Commenges, J. M. Gran +4
Highly active antiretroviral therapy (HAART) has proved efficient in increasing CD4 counts in many randomized clinical trials. Because randomized trials have some limitations (e.g.…
Inference in HIV dynamics models via hierarchical likelihood
D. Commenges, D. Jolly, H. Putter +1
HIV dynamical models are often based on non-linear systems of ordinary differential equations (ODE), which do not have analytical solution. Introducing random effects in such model…
Heterogeneous Viral Environment in a HIV Spatial Model
Claude-Michel Brauner, Danaelle Jolly, Luca Lorenzi +1
We consider the basic model of virus dynamics in the modeling of Human Immunodeficiency Virus (HIV), in a 2D heterogenous environment. It consists of two ODEs for the non-infected…