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- KTH Royal Institute of TechnologySE34 papers
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6 papers · 1 filter
Inferring Regulatory Networks by Combining Perturbation Screens and Steady State Gene Expression Profiles
Ali Shojaie, Alexandra Jauhiainen, Michael Kallitsis +1
Reconstructing transcriptional regulatory networks is an important task in functional genomics. Data obtained from experiments that perturb genes by knockouts or RNA interference c…
Natural CMT2 variation is associated with genome-wide methylation changes and temperature adaptation
Xia Shen, Simon Forsberg, Mats Pettersson +2
A central problem when studying adaptation to a new environment is the interplay between genetic variation and phenotypic plasticity. Arabidopsis thaliana has colonized a wide rang…
Nanoscale elucidation of Na,K-ATPase isoforms in dendritic spines
Thomas Liebmann, Hans Blom, Anita Aperia +1
The dimensions of neuronal synapses suggest that optical super-resolution imaging methods are necessary for thorough investigation of protein distributions and interactions. Nanosc…
Diffusion on networked systems is a question of time or structure
Jean-Charles Delvenne, Renaud Lambiotte, Luis E. C. Rocha
Network science investigates the architecture of complex systems to understand their functional and dynamical properties. Structural patterns such as communities shape diffusive pr…
kruX: Matrix-based non-parametric eQTL discovery
Jianlong Qi, Hassan Foroughi Asl, Johan Bjorkegren +1
The Kruskal-Wallis test is a popular non-parametric statistical test for identifying expression quantitative trait loci (eQTLs) from genome-wide data due to its robustness against…
Correlation of Automorphism Group Size and Topological Properties with Program-size Complexity Evaluations of Graphs and Complex Networks
Hector Zenil, Fernando Soler-Toscano, Kamaludin Dingle +1
We show that numerical approximations of Kolmogorov complexity (K) applied to graph adjacency matrices capture some group-theoretic and topological properties of graphs and empiric…