output
20032023
most citedCAR T cell therapy in B-cell acute lymphoblastic leukaemia: Insights from mathematical models

56 citations

6 papers

eess.IV2023★ 31 cited

Deep learning-based instance segmentation for the precise automated quantification of digital breast cancer immunohistochemistry images

Blanca Maria Priego-Torresa, Barbara Lobato-Delgado, Lidia Atienza-Cuevas +1

The quantification of biomarkers on immunohistochemistry breast cancer images is essential for defining appropriate therapy for breast cancer patients, as well as for extracting re…

q-bio.TO2020★ 29 cited

Mathematical models of Leukaemia and its treatment: A review

Salvador Chulián, Álvaro-Martínez Rubio, María Rosa +1

Leukaemia accounts for around 3% of all cancer types diagnosed in adults, and is the most common type of cancer in children of paediatric age. There is increasing interest in the u…

q-bio.TO2020

Dynamical properties of feedback signalling in B lymphopoiesis: A mathematical modelling approach

Salvador Chulián, Alvaro Martínez-Rubio, Anna Marciniak-Czochra +7

Haematopoiesis is the process of generation of blood cells. Lymphopoiesis generates lymphocytes, the cells in charge of the adaptive immune response. Disruptions of this process ar…

q-bio.TO2020★ 56 cited

CAR T cell therapy in B-cell acute lymphoblastic leukaemia: Insights from mathematical models

Odelaisy Leon-Triana, Soukaina Sabir, Gabriel F. Calvo +7

Immunotherapies use components of the patient immune system to selectively target cancer cells. The use of CAR T cells to treat B-cell malignancies --leukaemias and lymphomas-- is…

physics.med-ph2006★ 20 cited

Dose distribution in water for monoenergetic photon point sources in the energy range of interest in brachytherapy: Monte Carlo simulations with PENELOPE and GEANT4

Julio F. Almansa, Rafael Guerrero, Feras M. O. Al-Dweri +2

Monte Carlo calculations using the codes PENELOPE and GEANT4 have been performed to characterize the dosimetric properties of monoenergetic photon point sources in water. The dose…

physics.med-ph2003★ 24 cited

Dosimetry characterization of P intravascular brachytherapy source wires using Monte Carlo codes PENELOPE and GEANT4

Javier Torres, Manuel J. Buades, Julio F. Almansa +2

Monte Carlo calculations using the codes PENELOPE and GEANT4 have been performed to characterize the dosimetric parameters of the new 20 mm long catheter based P beta source…