433 citations · 3.4k across the 67 of their papers we have counts for
68 papers
Universal scaling laws rule explosive growth inhuman cancers
Víctor M. Pérez-García, Gabriel F. Calvo, Jesús J. Bosque +24
Most physical and other natural systems are complex entities composed of a large number of interacting individual elements. It is a surprising fact that they often obey the so-call…
Mathematical models of Leukaemia and its treatment: A review
Salvador Chulián, Álvaro-Martínez Rubio, María Rosa +1
Leukaemia accounts for around 3% of all cancer types diagnosed in adults, and is the most common type of cancer in children of paediatric age. There is increasing interest in the u…
Dynamical properties of feedback signalling in B lymphopoiesis: A mathematical modelling approach
Salvador Chulián, Alvaro Martínez-Rubio, Anna Marciniak-Czochra +7
Haematopoiesis is the process of generation of blood cells. Lymphopoiesis generates lymphocytes, the cells in charge of the adaptive immune response. Disruptions of this process ar…
CAR T cell therapy in B-cell acute lymphoblastic leukaemia: Insights from mathematical models
Odelaisy Leon-Triana, Soukaina Sabir, Gabriel F. Calvo +7
Immunotherapies use components of the patient immune system to selectively target cancer cells. The use of CAR T cells to treat B-cell malignancies --leukaemias and lymphomas-- is…
A mathematical model of low grade gliomas treated with temozolomide and its therapeutical implications
Magdalena U. Bogdańska, Marek Bodnar, Juan Belmonte-Beitia +4
Low grade gliomas (LGGs) are infiltrative and incurable primary brain tumours with typically slow evolution. These tumours usually occur in young and otherwise healthy patients, br…
Extreme protraction for low grade gliomas: Theoretical proof of concept of a novel therapeutical strategy
Victor M. Perez-Garcia
Grade II gliomas are slowly growing primary brain tumors that affect mostly young patients and become fatal after a few years. Current clinical handling includes surgery as first l…