56 citations · 85 across the 4 of their papers we have counts for
4 papers
Understanding the role of B-cells in CAR T-cell therapy in leukemia through a mathematical model
Sergio Serrano, Roberto Barrio, Álvaro Martínez-Rubio +2
Chimeric Antigen Receptor T (CAR-T) cell therapy has been proven to be successful against different leukaemias and lymphomas. This paper makes an analytical and numerical study of…
Mathematical models of Leukaemia and its treatment: A review
Salvador Chulián, Álvaro-Martínez Rubio, María Rosa +1
Leukaemia accounts for around 3% of all cancer types diagnosed in adults, and is the most common type of cancer in children of paediatric age. There is increasing interest in the u…
Dynamical properties of feedback signalling in B lymphopoiesis: A mathematical modelling approach
Salvador Chulián, Alvaro Martínez-Rubio, Anna Marciniak-Czochra +7
Haematopoiesis is the process of generation of blood cells. Lymphopoiesis generates lymphocytes, the cells in charge of the adaptive immune response. Disruptions of this process ar…
CAR T cell therapy in B-cell acute lymphoblastic leukaemia: Insights from mathematical models
Odelaisy Leon-Triana, Soukaina Sabir, Gabriel F. Calvo +7
Immunotherapies use components of the patient immune system to selectively target cancer cells. The use of CAR T cells to treat B-cell malignancies --leukaemias and lymphomas-- is…