output
20202025
most citedCAR T cell therapy in B-cell acute lymphoblastic leukaemia: Insights from mathematical models

56 citations

8 papers

cs.HC2025★ 10 cited

Smart Device Development for Gait Monitoring: Multimodal Feedback in an Interactive Foot Orthosis, Walking Aid, and Mobile Application

Stefan Resch, André Kousha, Anna Carroll +5

Smart assistive technologies such as sensor-based footwear and walking aids offer promising opportunities for gait rehabilitation through real-time feedback and patient-centered mo…

eess.IV2023★ 31 cited

Deep learning-based instance segmentation for the precise automated quantification of digital breast cancer immunohistochemistry images

Blanca Maria Priego-Torresa, Barbara Lobato-Delgado, Lidia Atienza-Cuevas +1

The quantification of biomarkers on immunohistochemistry breast cancer images is essential for defining appropriate therapy for breast cancer patients, as well as for extracting re…

cond-mat.mes-hall2022★ 15 cited

Estimating the heating of complex nanoparticle aggregates for magnetic hyperthermia

Javier Ortega Julia, Daniel Ortega, Jonathan Leliaert

Understanding and predicting the heat released by magnetic nanoparticles is central to magnetic hyperthermia treatment planning. These nanoparticles tend to form aggregates when in…

physics.med-ph2022★ 1 cited

Polarimetric imaging for the detection of synthetic models of SARS-CoV-2: a proof of concept

Emilio Gomez-Gonzalez, Olga Muñoz, Juan Carlos Gomez-Martin +23

Objective: To conduct a proof-of-concept study of the detection of two synthetic models of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) using polarimetric imaging.…

q-bio.TO2020★ 29 cited

Mathematical models of Leukaemia and its treatment: A review

Salvador Chulián, Álvaro-Martínez Rubio, María Rosa +1

Leukaemia accounts for around 3% of all cancer types diagnosed in adults, and is the most common type of cancer in children of paediatric age. There is increasing interest in the u…

q-bio.TO2020

Dynamical properties of feedback signalling in B lymphopoiesis: A mathematical modelling approach

Salvador Chulián, Alvaro Martínez-Rubio, Anna Marciniak-Czochra +7

Haematopoiesis is the process of generation of blood cells. Lymphopoiesis generates lymphocytes, the cells in charge of the adaptive immune response. Disruptions of this process ar…

q-bio.TO2020★ 43 cited

CAR T cells for T-cell leukemias: Insights from mathematical models

Víctor M. Pérez-García, O. León-Triana, M. Rosa +1

Immunotherapy has the potential to change the way all cancer types are treated and cured. Cancer immunotherapies use elements of the patient immune system to attack tumor cells. On…

q-bio.TO2020★ 56 cited

CAR T cell therapy in B-cell acute lymphoblastic leukaemia: Insights from mathematical models

Odelaisy Leon-Triana, Soukaina Sabir, Gabriel F. Calvo +7

Immunotherapies use components of the patient immune system to selectively target cancer cells. The use of CAR T cells to treat B-cell malignancies --leukaemias and lymphomas-- is…