output
20102025
most citedDetecting T-cell receptors involved in immune responses from single repertoire snapshots

159 citations

17 papers

q-bio.GN2025

scRNA-seq of preeclamptic trophoblasts identifies EBI3, COL17A1, miR-27a-5p, and miR-193b-5p as hypoxia markers: validation of neuradapt as a superior mimetic to cobalt chloride

Evgeny Knyazev, Timur Kulagin, Ivan Antipenko +1

Background. Preeclampsia (PE) complicates 2-8% of pregnancies and involves placental hypoxia and HIF-pathway activation, especially in early-onset PE (eoPE). Chemical mimetics like…

astro-ph.EP2024★ 1 cited

Orbital maneuvers for a space probe around Titania

Jadilene Xavier, Antônio Bertachini, Silvia Giuliatti Winter +1

For most space missions, it is interesting that the probe remains for a considerable time around the mission target. The longer the lifetime of a mission, the greater the chances o…

physics.optics2023★ 34 cited

Topological Darkness: How to Design a Metamaterial for Optical Biosensing with Virtually Unlimited Sensitivity

G. Tselikov, A. Danilov, V. O. Shipunova +3

Due to the absence of labels and fast analyses, optical biosensors promise major advances in biomedical diagnostics, security, environmental and food safety applications. However,…

q-bio.BM2022★ 28 cited

NMR spectrum reconstruction as a pattern recognition problem

Amir Jahangiri, Xiao Han, Dmitry Lesovoy +4

A new deep neural network based on the WaveNet architecture (WNN) is presented, which is designed to grasp specific patterns in the NMR spectra. When trained at a fixed non-uniform…

cond-mat.mes-hall2021★ 13 cited

Strong exciton-photon coupling with colloidal quantum dots in a tuneable microcavity

Dmitriy Dovzhenko, Maksim Lednev, Konstantin Mochalov +4

Polariton emission from optical cavities integrated with various luminophores has been extensively studied recently due to the wide variety of possible applications in photonics, p…

math.DS2020

A deterministic model for non-monotone relationship between translation of upstream and downstream open reading frames

D. E. Andreev, P. V. Baranov, A. Milogorodskii +1

TASEP modeling was shown to offer a parsimonious explanation for the experimentally confirmed ability of a single upstream Open Reading Frames (uORFs) to upregulate downstream tran…

cond-mat.mes-hall2020

Polariton-assisted donor-acceptor role reversal in resonant energy transfer between organic dyes strongly coupled to electromagnetic modes of a tuneable microcavity

Dmitriy Dovzhenko, Maksim Lednev, Konstantin Mochalov +3

Resonant interaction between excitonic transitions of molecules and localized electromagnetic field allows the formation of hybrid light-matter polaritonic states. This hybridizati…

q-bio.GN2020★ 18 cited

Immune Fingerprinting through Repertoire Similarity

Thomas Dupic, Meriem Bensouda Koraichi, Anastasia Minervina +3

Immune repertoires provide a unique fingerprint reflecting the immune history of individuals, with potential applications in precision medicine. However, the question of how person…

q-bio.GN2020★ 153 cited

Longitudinal high-throughput TCR repertoire profiling reveals the dynamics of T cell memory formation after mild COVID-19 infection

Anastasia A. Minervina, Ekaterina A. Komech, Aleksei Titov +10

COVID-19 is a global pandemic caused by the SARS-CoV-2 coronavirus. T cells play a key role in the adaptive antiviral immune response by killing infected cells and facilitating the…

q-bio.GN2019★ 73 cited

Primary and secondary anti-viral response captured by the dynamics and phenotype of individual T cell clones

Anastasia A. Minervina, Mikhail V. Pogorelyy, Ekaterina A. Komech +9

The diverse repertoire of T-cell receptors (TCR) plays a key role in the adaptive immune response to infections. Previous studies show that secondary responses to the yellow fever…

q-bio.QM2019★ 18 cited

A minimum set of stable blocks for rational design of polypeptide chains Running head: A set of stable blocks for protein rational design

Alexei Nekrasov, Ludmila Alekseeva, Rudolf A. Pogosyan +4

The aim of this work was to find a minimal set of structurally stable pentapeptides, which allows forming a polypeptide chain of a required 3D structure. To search for factors that…

q-bio.GN2018★ 159 cited

Detecting T-cell receptors involved in immune responses from single repertoire snapshots

Mikhail V Pogorelyy, Anastasia A Minervina, Mikhail Shugay +4

Hypervariable T-cell receptors (TCR) play a key role in adaptive immunity, recognising a vast diversity of pathogen-derived antigens. High throughput sequencing of TCR repertoires…

q-bio.PE2018★ 145 cited

Precise tracking of vaccine-responding T-cell clones reveals convergent and personalized response in identical twins

Mikhail V. Pogorelyy, Anastasia A. Minervina, Maximilian Puelma Touzel +11

T-cell receptor (TCR) repertoire data contain information about infections that could be used in disease diagnostics and vaccine development, but extracting that information remain…

q-bio.GN2017★ 72 cited

Method for identification of condition-associated public antigen receptor sequences

Mikhail V. Pogorelyy, Anastasia A. Minervina, Dmitriy M. Chudakov +4

Diverse repertoires of hypervariable immunoglobulin receptors (TCR and BCR) recognize antigens in the adaptive immune system. The development of immunoglobulin receptor repertoire…

q-bio.PE2016★ 107 cited

Persisting fetal clonotypes influence the structure and overlap of adult human T cell receptor repertoires

Mikhail V. Pogorelyy, Yuval Elhanati, Quentin Marcou +9

The diversity of T-cell receptors recognizing foreign pathogens is generated through a highly stochastic recombination process, making the independent production of the same sequen…

cond-mat.mes-hall2012★ 4 cited

Long range electronic tranport in DNA molecules deposited across a disconnected array of metallic nanoparticles

A. D. Chepelianskii, D. Klinov, A. Kasumov +4

We report in detail our experiments on the conduction of DNA molecules over a wide range of temperature deposited across slits in a few nanometers thick platinum film. These in…

cond-mat.mes-hall2010★ 14 cited

Conduction of DNA molecules attached to a disconnected array of metallic Ga nanoparticles

A. D. Chepelianskii, D. Klinov, A. Kasumov +4

We have investigated the conduction over a wide range of temperature of DNA molecules deposited across slits etched through a few nanometers thick platinum film. The slits are…