3 papers
q-bio.MN2020
Identification of Biomarkers Controlling Cell Fate In Blood Cell Development
Maryam Nazarieh, Volkhard Helms, Marc P. Hoeppner +1
A blood cell lineage consists of several consecutive developmental stages from the pluri- or multipotent stem cell to a state of terminal differentiation. Despite their importance…
q-bio.GN2020
Longitudinal high-throughput TCR repertoire profiling reveals the dynamics of T cell memory formation after mild COVID-19 infection
Anastasia A. Minervina, Ekaterina A. Komech, Aleksei Titov +10
COVID-19 is a global pandemic caused by the SARS-CoV-2 coronavirus. T cells play a key role in the adaptive antiviral immune response by killing infected cells and facilitating the…
q-bio.GN2019
Primary and secondary anti-viral response captured by the dynamics and phenotype of individual T cell clones
Anastasia A. Minervina, Mikhail V. Pogorelyy, Ekaterina A. Komech +9
The diverse repertoire of T-cell receptors (TCR) plays a key role in the adaptive immune response to infections. Previous studies show that secondary responses to the yellow fever…