4 citations
4 papers
SMART-MC: Characterizing the Dynamics of Multiple Sclerosis Therapy Transitions Using a Covariate-Based Markov Model
Beomchang Kim, Zongqi Xia, Priyam Das
Treatment switching is a common occurrence in the management of Multiple Sclerosis (MS), where patients transition across various disease-modifying therapies (DMTs) due to heteroge…
Alleviating Spatial Confounding in Spatial Frailty Models
Douglas Roberto Mesquita Azevedo, Marcos Oliveira Prates, Dipankar Bandyopadhyay
Spatial confounding is how is called the confounding between fixed and spatial random effects. It has been widely studied and it gained attention in the past years in the spatial s…
Immunological determinants of clinical outcomes in COVID-19: A quantitative perspective
Elizabeth Krieger, Nicole Vissichelli, Stefan Leichtle +13
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has a variable clinical presentation that ranges from asymptomatic, to severe disease with cytokine storm. The mortalit…
On the Order of Gene Distribution on Chromosomes Across the Animal Kingdom
Abdullah A. Toor, Amir A. Toor MD
Background. The large-scale pattern of distribution of genes on the chromosomes in the known animal genomes is not well characterized. We hypothesized that individual genes will be…