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20042026
most citedCell Detection with Star-convex Polygons

1.7k citations

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23 papers · 1 filter

physics.bio-ph2025★ 1 cited

TopoSPAM: Topology grounded Simulation Platform for morphogenesis and biological Active Matter

Abhinav Singh, Abhijeet Krishna, Aboutaleb Amiri +11

We present a topology grounded, multiscale simulation platform for morphogenesis and biological active matter. Morphogenesis and biological active matter represent keystone problem…

physics.bio-ph2025★ 22 cited

Measurements of molecular size and shape on a chip

Xin Zhu, Timothy JD Bennett, Konstantin C Zouboulis +6

Size and shape are critical discriminators between molecular species and states. We describe a micro-chip based high-throughput imaging approach offering rapid and precise determin…

physics.bio-ph2025★ 6 cited

A model for boundary-driven tissue morphogenesis

Daniel S. Alber, Shiheng Zhao, Alexandre O. Jacinto +3

Tissue deformations during morphogenesis can be active, driven by internal processes, or passive, resulting from stresses applied at their boundaries. Here, we introduce the Drosop…

physics.bio-ph2024★ 1 cited

Cell divisions imprint long lasting elastic strain fields in epithelial tissues

Ali Tahaei, Romina Pisticello-Gómez, S Suganthan +4

A hallmark of biological tissues, viewed as complex cellular materials, is the active generation of mechanical stresses by cellular processes, such as cell divisions. Each cellular…

physics.bio-ph2023★ 4 cited

Active shape control by plants in dynamic environments

Hadrien Oliveri, Derek E. Moulton, Heather A. Harrington +1

Plants are a paradigm for active shape control in response to stimuli. For instance, it is well-known that a tilted plant will eventually straighten vertically, demonstrating the i…

physics.bio-ph2021★ 30 cited

Active T1 transitions in cellular networks

Charlie Duclut, Joris Paijmans, Mandar M. Inamdar +2

In amorphous solids as in tissues, neighbor exchanges can relax local stresses and allow the material to flow. In this paper, we use an anisotropic vertex model to study T1 rearran…

physics.bio-ph2021★ 10 cited

Physical requirements for scaling up network-based biocomputation

Jingyuan Zhu, Till Korten, Hillel Kugler +5

The high energy consumption of electronic data processors, together with physical challenges limiting their further improvement, has triggered intensive interest in alternative com…

physics.bio-ph2021★ 12 cited

Molecular Assembly Lines in Active Droplets

Tyler S. Harmon, Frank Jülicher

Large protein complexes are assembled from protein subunits to form a specific structure. In our theoretic work, we propose that assembly into the correct structure could be reliab…

physics.bio-ph2020★ 144 cited

Generalized models for bond percolation transitions of associative polymers

Jeong-Mo Choi, Anthony A. Hyman, Rohit V. Pappu

Associative polymers with sticker-and-spacer architectures undergo phase transitions that combine phase separation and bond percolation. Here, we generalize mean-field models for b…

physics.bio-ph2019★ 5 cited

How to Pare a Pair: Topology Control and Pruning in Intertwined Complex Networks

Felix Kramer, Carl D. Modes

Recent work on self-organized remodeling of vasculature in slime-mold, leaf venation systems and vessel systems in vertebrates has put forward a plethora of potential adaptation me…

physics.bio-ph2018★ 22 cited

Limited Resources Induce Bistability in Microtubule Length Regulation

Matthias Rank, Aniruddha Mitra, Louis Reese +2

The availability of protein is an important factor for the determination of the size of the mitotic spindle. Involved in spindle-size regulation is kinesin-8, a molecular motor and…

physics.bio-ph2017★ 339 cited

The 2015 super-resolution microscopy roadmap

Stefan Hell, Steffen Sahl, Mark Bates +24

Far-field optical microscopy using focused light is an important tool in a number of scientific disciplines including chemical, (bio)physical and biomedical research, particularly…

physics.bio-ph2017★ 32 cited

Biobeam - Rigorous wave-optical simulations of light-sheet microscopy

Martin Weigert, Eugene W. Myers, Moritz Kreysing

Sample-induced image-degradation remains an intricate wave-optical problem in light-sheet microscopy. Here we present biobeam, an open-source software package that enables to simul…

physics.bio-ph2016★ 56 cited

Active dynamics of tissue shear flow

Marko Popović, Amitabha Nandi, Matthias Merkel +4

We present a hydrodynamic theory to describe shear flows in developing epithelial tissues. We introduce hydrodynamic fields corresponding to state properties of constituent cells a…

physics.bio-ph2016★ 200 cited

Stochastic resetting in backtrack recovery by RNA polymerases

Édgar Roldán, Ana Lisica, Daniel Sánchez-Taltavull +1

Transcription is a key process in gene expression, in which RNA polymerases produce a complementary RNA copy from a DNA template. RNA polymerization is frequently interrupted by ba…

physics.bio-ph2016★ 493 cited

Growth and Division of Active Droplets: A Model for Protocells

David Zwicker, Rabea Seyboldt, Christoph A. Weber +2

It has been proposed that during the early steps in the origin of life, small droplets could have formed via the segregation of molecules from complex mixtures by phase separation.…

physics.bio-ph2016★ 54 cited

Model for probing membrane-cortex adhesion by micropipette aspiration and fluctuation spectroscopy

Ricard Alert, Jaume Casademunt, Jan Brugués +1

We propose a model for membrane-cortex adhesion which couples membrane deformations, hydrodynamics and kinetics of membrane-cortex ligands. In its simplest form, the model gives ex…

physics.bio-ph2015★ 116 cited

Determining physical properties of the cell cortex

A. Saha, M. Nishikawa, M. Behrndt +3

Actin and myosin assemble into a thin layer of a highly dynamic network underneath the membrane of eukaryotic cells. This network generates the forces that drive cell and tissue-sc…

physics.bio-ph2014★ 30 cited

Motor regulation results in distal forces that bend partially disintegrated Chlamydomonas axonemes into circular arcs

V. Mukundan, P. Sartori, V. F. Geyer +2

The bending of cilia and flagella is driven by forces generated by dynein motor proteins. These forces slide adjacent microtubule doublets within the axoneme, the motile cytoskelet…

physics.bio-ph2012★ 1 cited

Thin Films of Chiral Motors

Maria Strempel, Sebastian Fürthauer, Stephan W. Grill +1

Hydrodynamic flows in biological systems are often generated by active chiral processes near or on surfaces. Important examples are beating cilia, force generation in actomyosin ne…

physics.bio-ph2010★ 46 cited

Mobility induces global synchronization of oscillators in periodic extended systems

Fernando Peruani, Ernesto M. Nicola, Luis G. Morelli

We study synchronization of locally coupled noisy phase oscillators which move diffusively in a one-dimensional ring. Together with the disordered and the globally synchronized sta…

physics.bio-ph2006★ 12 cited

Brownian Motion after Einstein: Some new applications and new experiments

David Selmeczi, Simon F. Tolic-Norrelykke, Erik Schaeffer +5

The first half of this chapter describes the development in mathematical models of Brownian motion after Einstein's seminal papers and current applications to optical tweezers. Thi…

physics.bio-ph2006★ 331 cited

Calibration of optical tweezers with positional detection in the back-focal-plane

Simon F. Tolic-Norrelykke, Erik Schaeffer, Jonathon Howard +3

We explain and demonstrate a new method of force- and position-calibration for optical tweezers with back-focal-plane photo detection. The method combines power spectral measuremen…