157 citations
- Université Paris CitéFR9 papers
- Centre de Recherche Épidémiologie et StatistiqueFR8 papers
- Assistance Publique – Hôpitaux de ParisFR7 papers
- InsermFR7 papers
- Sorbonne Paris CitéFR6 papers
- Centre National de la Recherche ScientifiqueFR3 papers
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'EnvironnementFR3 papers
- Université Sorbonne Paris NordFR3 papers
- Délégation Paris 5FR2 papers
- Laboratoire de Probabilités et Modèles AléatoiresFR2 papers
- Laboratoire de Probabilités, Statistique et ModélisationFR2 papers
- Sommeil, vigilance, fatigue et santé publiqueFR2 papers
14 papers
Evaluating virtual-control-augmented trials for reproducing treatment effect from original RCTs
Alex Fernandes, Raphaël Porcher, Viet-Thi Tran +1
This study investigates the use of virtual patient data to augment control arms in randomised controlled trials (RCTs). Using data from the IST and IST3 trials, we simulated RCTs i…
Why does tinnitus vary with naps? A polysomnographic prospective study exploring the somatosensory hypothesis
Robin Guillard, Vincent Philippe, Adam Hessas +6
Background: Tinnitus, defined as the conscious awareness of a noise without any identifiable corresponding external acoustic source, can be modulated by various factors. Among thes…
Real-world validation of a multimodal LLM-powered pipeline for High-Accuracy Clinical Trial Patient Matching leveraging EHR data
Anatole Callies, Quentin Bodinier, Philippe Ravaud +1
Background: Patient recruitment in clinical trials is hindered by complex eligibility criteria and labor-intensive chart reviews. Prior research using text-only models have struggl…
Optimal treatment regimes for the net benefit of a treatment
François Petit, Gérard Biau, Raphaël Porcher
We develop a mathematical framework to define an optimal individualized treatment rule (ITR) within the context of prioritized outcomes in a randomized controlled trial. Our optima…
Validation of a new, minimally-invasive, software smartphone device to predict sleep apnea and its severity: transversal study
Justine Frija, Juliette Millet, Emilie Bequignon +8
Obstructive sleep apnea (OSA) is frequent and responsible for cardiovascular complications and excessive daytime sleepiness. It is underdiagnosed due to the difficulty to access th…
Estimating Complier Average Causal Effects with Mixtures of Experts
François Grolleau, Céline Béji, Raphaël Porcher +1
Treatment non-compliance, where individuals deviate from their assigned experimental conditions, frequently complicates the estimation of causal effects. To address this, we introd…