157 citations
Counting papers with at most 25 authors, so collaboration author lists do not stand in for the people here.
- Université Paris CitéFR14 papers
- InsermFR12 papers
- Sorbonne Paris CitéFR10 papers
- Hôtel-Dieu de ParisFR8 papers
- Délégation Paris 5FR5 papers
- Assistance Publique – Hôpitaux de ParisFR3 papers
- École des Hautes Études en Santé PubliqueFR3 papers
- Centre Hospitalier Universitaire de Saint-ÉtienneFR2 papers
- Centre Inria de SaclayFR2 papers
- Centre National de la Recherche ScientifiqueFR2 papers
- Hôpital Paul-BrousseFR2 papers
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'EnvironnementFR2 papers
17 papers
Evaluating virtual-control-augmented trials for reproducing treatment effect from original RCTs
Alex Fernandes, Raphaël Porcher, Viet-Thi Tran +1
This study investigates the use of virtual patient data to augment control arms in randomised controlled trials (RCTs). Using data from the IST and IST3 trials, we simulated RCTs i…
Optimal treatment regimes for the net benefit of a treatment
François Petit, Gérard Biau, Raphaël Porcher
We develop a mathematical framework to define an optimal individualized treatment rule (ITR) within the context of prioritized outcomes in a randomized controlled trial. Our optima…
Meta-analysis models relaxing the random effects normality assumption: methodological systematic review and simulation study
Kanella Panagiotopoulou, Theodoros Evrenoglou, Christopher H Schmid +2
Random effects meta-analysis is widely used for synthesizing studies under the assumption that underlying effects come from a normal distribution. However, under certain conditions…
Clinical research and methodology What usage and what hierarchical order for secondary endpoints?
Silvy Laporte, Marine Diviné, Danièle Girault +12
In a randomised clinical trial, when the result of the primary endpoint shows a significant benefit, the secondary endpoints are scrutinised to identify additional effects of the t…
Estimating Complier Average Causal Effects with Mixtures of Experts
François Grolleau, Céline Béji, Raphaël Porcher +1
Treatment non-compliance, where individuals deviate from their assigned experimental conditions, frequently complicates the estimation of causal effects. To address this, we introd…
Primary liver cancer classification from routine tumour biopsy using weakly supervised deep learning
Aurélie Beaufrère, Nora Ouzir, Paul Emile Zafar +8
The diagnosis of primary liver cancers (PLCs) can be challenging, especially on biopsies and for combined hepatocellular-cholangiocarcinoma (cHCC-CCA). We automatically classified…
False discovery proportion envelopes with m-consistency
Iqraa Meah, Gilles Blanchard, Etienne Roquain
We provide new non-asymptotic false discovery proportion (FDP) confidence envelopes in several multiple testing settings relevant for modern high dimensional-data methods. We revis…
A Comprehensive Framework for the Evaluation of Individual Treatment Rules From Observational Data
François Grolleau, Francois Petit, Raphaël Porcher
Individualized treatment rules (ITRs) are deterministic decision rules that recommend treatments to individuals based on their characteristics. Though ubiquitous in medicine, ITRs…
Projected distances for multi-parameter persistence modules
Nicolas Berkouk, Francois Petit
Relying on sheaf theory, we introduce the notions of projected barcodes and projected distances for multi-parameter persistence modules. Projected barcodes are defined as derived p…
Stratified cross-validation for unbiased and privacy-preserving federated learning
R. Bey, R. Goussault, M. Benchoufi +1
Large-scale collections of electronic records constitute both an opportunity for the development of more accurate prediction models and a threat for privacy. To limit privacy expos…
A novel approach for identifying and addressing case-mix heterogeneity in individual participant data meta-analysis
Tat-Thang Vo, Raphael Porcher, Anna Chaimani +1
Case-mix heterogeneity across studies complicates meta-analyses. As a result of this, treatments that are equally effective on patient subgroups may appear to have different effect…
Cord-blood vitamin D level and night sleep duration in preschoolers in the EDEN mother-child birth cohort
Chu Yan Yong, Eve Reynaud, Anne Forhan +4
Objective: 25-hydroxyvitamin D (25OHD) deficiency has been associated with sleep disorders in adults. Only three cross-sectional studies were performed in children and showed an as…
Association of night-waking and inattention/hyperactivity symptoms trajectories in preschool-aged children
Eve Reynaud, Anne Forhan, Barbara Heude +2
Objective: To study the longitudinal associations between inattention/hyperactivity symptoms and night-waking in preschool-years, in light of their joint evolution.Study design: Wi…
Night sleep duration trajectories and associated factors among preschool children from the EDEN cohort
Sabine Plancoulaine, Eve Reynaud, Anne Forhan +3
Objective. Sleep duration may vary inter-individually and intra-individually over time. We aimed at both identifying night-sleep duration (NSD) trajectories among preschoolers and…
Sleep and its relation to cognition and behaviour in preschool-aged children of the general population: a systematic review
Eve Reynaud, Marie-Françoise Vecchierini, Barbara Heude +2
Background: While the relations between sleep, cognition and behavior have been extensively studied in adolescents and school-aged children, very little attention has been given to…
Early features associated with the neurocognitive development at 36 months of age: the AuBE study
Sabine Plancoulaine, Camille Stagnara, Sophie Flori +4
Background. Few studies on the relations between sleep quantity and/or quality and cognition were conducted among pre-schoolers from healthy general population. We aimed at identif…
Ephemeral persistence modules and distance comparison
Nicolas Berkouk, Francois Petit
We provide a definition of ephemeral multi-persistent modules and prove that the quotient of persistent modules by the ephemeral ones is equivalent to the category of -sheaves.…