157 citations
- Université Paris CitéFR9 papers
- Centre de Recherche Épidémiologie et StatistiqueFR8 papers
- Assistance Publique – Hôpitaux de ParisFR7 papers
- InsermFR7 papers
- Sorbonne Paris CitéFR6 papers
- Centre National de la Recherche ScientifiqueFR3 papers
- Institut National de Recherche pour l'Agriculture, l'Alimentation et l'EnvironnementFR3 papers
- Université Sorbonne Paris NordFR3 papers
- Délégation Paris 5FR2 papers
- Laboratoire de Probabilités et Modèles AléatoiresFR2 papers
- Laboratoire de Probabilités, Statistique et ModélisationFR2 papers
- Sommeil, vigilance, fatigue et santé publiqueFR2 papers
4 papers · 1 filter
Evaluating virtual-control-augmented trials for reproducing treatment effect from original RCTs
Alex Fernandes, Raphaël Porcher, Viet-Thi Tran +1
This study investigates the use of virtual patient data to augment control arms in randomised controlled trials (RCTs). Using data from the IST and IST3 trials, we simulated RCTs i…
Optimal treatment regimes for the net benefit of a treatment
François Petit, Gérard Biau, Raphaël Porcher
We develop a mathematical framework to define an optimal individualized treatment rule (ITR) within the context of prioritized outcomes in a randomized controlled trial. Our optima…
Estimating Complier Average Causal Effects with Mixtures of Experts
François Grolleau, Céline Béji, Raphaël Porcher +1
Treatment non-compliance, where individuals deviate from their assigned experimental conditions, frequently complicates the estimation of causal effects. To address this, we introd…
A Comprehensive Framework for the Evaluation of Individual Treatment Rules From Observational Data
François Grolleau, Francois Petit, Raphaël Porcher
Individualized treatment rules (ITRs) are deterministic decision rules that recommend treatments to individuals based on their characteristics. Though ubiquitous in medicine, ITRs…