116 citations
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q-bio.TO2019★ 54 cited
Universality of clone dynamics during tissue development
Steffen Rulands, Fabienne Lescroart, Samira Chabab +7
The emergence of complex organs is driven by the coordinated proliferation, migration and differentiation of precursor cells. The fate behaviour of these cells is reflected in the…
q-bio.TO2017★ 3 cited
Extreme value statistics of mutation accumulation in renewing cell populations
Philip Greulich, Benjamin D. Simons
The emergence of a predominant phenotype within a cell population is often triggered by a rare accumulation of DNA mutations in a single cell. For example, tumors may be initiated…