140 citations
Counting papers with at most 25 authors, so collaboration author lists do not stand in for the people here.
- Pennsylvania State UniversityUS11 papers
- National Institutes of HealthUS2 papers
- University of North Carolina at Chapel HillUS2 papers
- Albany State UniversityUS1 paper
- Albert Einstein College of MedicineUS1 paper
- Boston Medical CenterUS1 paper
- Boston UniversityUS1 paper
- Cal HumanitiesUS1 paper
- Center for Neuro-OncologyUS1 paper
- Cincinnati Children's Hospital Medical CenterUS1 paper
- Clinical Research InstituteUS1 paper
- Columbia UniversityUS1 paper
15 papers
Epidemic Informatics and Control: A Holistic Approach from System Informatics to Epidemic Response and Risk Management in Public Health
Hui Yang, Siqi Zhang, Runsang Liu +4
This paper presents a holistic systems informatics approach, i.e., Define, Measure, Analyze, Improve, and Control (DMAIC), for epidemic response and management through the intensiv…
Optimal alignment of Lorentz orientation and generalization to matrix Lie groups
Congzhou M Sha
There exist elegant methods of aligning point clouds in . Unfortunately, these methods fail to generalize to the case of Minkowski space, as we will show. Instead, we…
Environment Scan of Generative AI Infrastructure for Clinical and Translational Science
Betina Idnay, Zihan Xu, William G. Adams +54
This study reports a comprehensive environmental scan of the generative AI (GenAI) infrastructure in the national network for clinical and translational science across 36 instituti…
Analysis of Gene Regulatory Networks from Gene Expression Using Graph Neural Networks
Hakan T. Otal, Abdulhamit Subasi, Furkan Kurt +2
Unraveling the complexities of Gene Regulatory Networks (GRNs) is crucial for understanding cellular processes and disease mechanisms. Traditional computational methods often strug…
Charting a finite element, mechanical atlas of dermatologic wound closure
Congzhou M Sha
Wound geometry and the mechanical properties of human skin govern the failure modes of partially healed or scarred tissue. Though dermatologists and surgeons develop an intuitive u…
Autofluorescence Bronchoscopy Video Analysis for Lesion Frame Detection
Qi Chang, Rebecca Bascom, Jennifer Toth +2
Because of the significance of bronchial lesions as indicators of early lung cancer and squamous cell carcinoma, a critical need exists for early detection of bronchial lesions. Au…
Differentiable Rotamer Sampling with Molecular Force Fields
Congzhou M. Sha, Jian Wang, Nikolay V. Dokholyan
Molecular dynamics is the primary computational method by which modern structural biology explores macromolecule structure and function. Boltzmann generators have been proposed as…
Accurate Virus Identification with Interpretable Raman Signatures by Machine Learning
Jiarong Ye, Yin-Ting Yeh, Yuan Xue +16
Rapid identification of newly emerging or circulating viruses is an important first step toward managing the public health response to potential outbreaks. A portable virus capture…
Selective Synthetic Augmentation with HistoGAN for Improved Histopathology Image Classification
Yuan Xue, Jiarong Ye, Qianying Zhou +7
Histopathological analysis is the present gold standard for precancerous lesion diagnosis. The goal of automated histopathological classification from digital images requires super…
A Note on Bayesian Modeling Specification of Censored Data in JAGS
Xinyue Qi, Shouhao Zhou, Martyn Plummer
Just Another Gibbs Sampling (JAGS) is a convenient tool to draw posterior samples using Markov Chain Monte Carlo for Bayesian modeling. However, the built-in function dinterval() t…
ET-Lasso: A New Efficient Tuning of Lasso-type Regularization for High-Dimensional Data
Songshan Yang, Jiawei Wen, Xiang Zhan +1
The L1 regularization (Lasso) has proven to be a versatile tool to select relevant features and estimate the model coefficients simultaneously and has been widely used in many rese…
A robustified posterior for Bayesian inference on a large number of parallel effects
J G Liao, Arthur Berg, Timothy L McMurry
Many modern experiments, such as microarray gene expression and genome-wide association studies, present the problem of estimating a large number of parallel effects. Bayesian infe…
Separating Putative Pathogens from Background Contamination with Principal Orthogonal Decomposition: Evidence for Leptospira in the Ugandan Neonatal Septisome
Steven J. Schiff, Julius Kiwanuka, Gina Riggio +14
Neonatal sepsis (NS) is responsible for over a 1 million yearly deaths worldwide. In the developing world NS is often treated without an identified microbial pathogen. Amplicon seq…
A fast algorithm for detecting gene-gene interactions in genome-wide association studies
Jiahan Li, Wei Zhong, Runze Li +1
With the recent advent of high-throughput genotyping techniques, genetic data for genome-wide association studies (GWAS) have become increasingly available, which entails the devel…
Consistent Testing for Recurrent Genomic Aberrations
Vonn Walter, Fred A. Wright, Andrew B. Nobel
Genomic aberrations, such as somatic copy number alterations, are frequently observed in tumor tissue. Recurrent aberrations, occurring in the same region across multiple subjects,…