output
19982025
most citedSecond-generation PLINK: rising to the challenge of larger and richer datasets

14.3k citations

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9 papers · 1 filter

stat.AP2024★ 3 cited

Hierarchical Bayesian estimation of motor-evoked potential recruitment curves yields accurate and robust estimates

Vishweshwar Tyagi, Lynda M. Murray, Ahmet S. Asan +5

Electromagnetic stimulation probes and modulates the neural systems that control movement. Key to understanding their effects is the muscle recruitment curve, which maps evoked pot…

stat.AP2022★ 4 cited

Analyzing Population-Level Trials as N-of-1 Trials: an Application to Gait

Lin Zhou, Juliana Schneider, Bert Arnrich +1

Studying individual causal effects of health interventions is of interest whenever intervention effects are heterogeneous between study participants. Conducting N-of-1 trials, whic…

stat.AP2020

GEE-TGDR: A longitudinal feature selection algorithm and its application to lncRNA expression profiles for psoriasis patients treated with immune therapies

Suyan Tian, Chi Wang, Mayte Suarez-Farinas

With the fast evolution of high-throughput technology, longitudinal gene expression experiments have become affordable and increasingly common in biomedical fields. Generalized est…

stat.AP2020★ 78 cited

Estimating heterogeneous survival treatment effect in observational data using machine learning

Liangyuan Hu, Jiayi Ji, Fan Li

Methods for estimating heterogeneous treatment effect in observational data have largely focused on continuous or binary outcomes, and have been relatively less vetted with surviva…

stat.AP2019

Modeling the Causal Effect of Treatment Initiation Time on Survival: Application to HIV/TB Co-infection

Liangyuan Hu, Joseph W. Hogan, Ann W. Mwangi +1

The timing of antiretroviral therapy (ART) initiation for HIV and tuberculosis (TB) co-infected patients needs to be considered carefully. CD4 cell count can be used to guide decis…

stat.AP2019★ 3 cited

Causal comparative effectiveness analysis of dynamic continuous-time treatment initiation rules with sparsely measured outcomes and death

Liangyuan Hu, Joseph W. Hogan

Evidence supporting the current World Health Organization recommendations of early antiretroviral therapy (ART) initiation for adolescents is inconclusive. We leverage a large obse…

stat.AP2019★ 37 cited

Kernel Machine and Distributed Lag Models for Assessing Windows of Susceptibility to Environmental Mixtures in Children's Health Studies

Ander Wilson, Hsiao-Hsien Leon Hsu, Yueh-Hsiu Mathilda Chiu +3

Exposures to environmental chemicals during gestation can alter health status later in life. Most studies of maternal exposure to chemicals during pregnancy have focused on a singl…

stat.AP2019★ 27 cited

Genomics models in radiotherapy: from mechanistic to machine learning

John Kang, James T. Coates, Robert L. Strawderman +2

Machine learning provides a broad framework for addressing high-dimensional prediction problems in classification and regression. While machine learning is often applied for imagin…

stat.AP2019★ 20 cited

Gaussian Markov Random Fields versus Linear Mixed Models for satellite-based PM2.5 assessment: Evidence from the Northeastern USA

Ron Sarafian, Itai Kloog, Allan C. Just +1

Studying the effects of air-pollution on health is a key area in environmental epidemiology. An accurate estimation of air-pollution effects requires spatio-temporally resolved dat…