457 citations
- Universitat Pompeu FabraES7 papers
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4 papers · 1 filter
Origins of de novo genes in human and chimpanzee
Jorge Ruiz-Orera, Jessica Hernandez-Rodriguez, Cristina Chiva +5
The birth of new genes is an important motor of evolutionary innovation. Whereas many new genes arise by gene duplication, others originate at genomic regions that do not contain a…
The genomic landscape of meiotic crossovers and gene conversions in Arabidopsis thaliana
Erik Wijnker, Geo Velikkakam James, Jia Ding +14
Knowledge of the exact distribution of meiotic crossovers (COs) and gene conversions (GCs) is essential for understanding many aspects of population genetics and evolution, from ha…
CTCF-mediated transcriptional regulation through cell type-specific chromosome organization in the β-globin locus
Ivan Junier, Ryan Dale, Chunhui Hou +2
The principles underlying the architectural landscape of chromatin beyond the nucleosome level in living cells remains largely unknown despite its potential to play a role in mamma…
Faster exact Markovian probability functions for motif occurrences: a DFA-only approach
Paolo Ribeca, Emanuele Raineri
Background: The computation of the statistical properties of motif occurrences has an obviously relevant practical application: for example, patterns that are significantly over- o…